Evidence map›Paper›PMID 29549363›Full record

ArticleScientific reports2018

Mapping the virome in wild-caught Aedes aegypti from Cairns and Bangkok.

Martha Zakrzewski, Gordana Rašić, Jonathan Darbro, Lutz Krause, Yee S Poo, Igor Filipović, Rhys Parry, Sassan Asgari, Greg Devine, Andreas Suhrbier

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Vector competence acrossJournal of virology · 2026
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  4. Microbiota variation inMicrobiology spectrum · 2026
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  7. Viruses · 2026
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Martha ZakrzewskiMedical Genomics, QIMR Berghofer Medical Research Institute, Brisbane, Qld, 4029, Australia.
Gordana RašićMosquito Control, QIMR Berghofer Medical Research Institute, Brisbane, Qld, 4029, Australia.
Jonathan DarbroMosquito Control, QIMR Berghofer Medical Research Institute, Brisbane, Qld, 4029, Australia.
Lutz KrauseMedical Genomics, QIMR Berghofer Medical Research Institute, Brisbane, Qld, 4029, Australia.ORCID 0000-0003-3806-0845
Yee S PooInflammation Biology, QIMR Berghofer Medical Research Institute, Brisbane, Qld, 4029, Australia.
Igor FilipovićMosquito Control, QIMR Berghofer Medical Research Institute, Brisbane, Qld, 4029, Australia.ORCID 0000-0001-9790-5639
Rhys ParrySchool of Biological Sciences, The University of Queensland, Brisbane, QLD, 4029, Australia.
Sassan AsgariSchool of Biological Sciences, The University of Queensland, Brisbane, QLD, 4029, Australia.ORCID 0000-0001-7885-6544
Greg DevineMosquito Control, QIMR Berghofer Medical Research Institute, Brisbane, Qld, 4029, Australia.
Andreas SuhrbierInflammation Biology, QIMR Berghofer Medical Research Institute, Brisbane, Qld, 4029, Australia. Andreas.Suhrbier@qimrberghofer.edu.au.ORCID 0000-0001-8986-9025
QIMR Berghofer Medical Research Institute · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medically important arboviruses such as dengue, Zika, and chikungunya viruses are primarily transmitted by the globally distributed mosquito Aedes aegypti. Increasing evidence suggests that transmission can be influenced by mosquito viromes. Herein RNA-Seq was used to characterize RNA metaviromes of wild-caught Ae. aegypti from Bangkok (Thailand) and from Cairns (Australia). The two mosquito populations showed a high degree of similarity in their viromes. BLAST searches of assembled contigs suggest up to 27 insect-specific viruses may infect Ae. aegypti, with up to 23 of these currently uncharacterized and up to 16 infecting mosquitoes from both Cairns and Bangkok. Three characterized viruses dominated, Phasi Charoen-like virus, Humaita-Tubiacanga virus and Cell fusing agent virus, and comparisons with other available RNA-Seq datasets suggested infection levels with these viruses may vary in laboratory-reared mosquitoes. As expected, mosquitoes from Bangkok showed higher mitochondrial diversity and carried alleles associated with knock-down resistance to pyrethroids. Blood meal reads primarily mapped to human genes, with a small number also showing homology with rat/mouse and dog genes. These results highlight the wide spectrum of data that can be obtained from such RNA-Seq analyses, and suggests differing viromes may need to be considered in arbovirus vector competence studies.

Indexed as

AedesAnimalsAustraliaBacteriaDrug ResistanceFungiInsect VirusesMitochondriaPolymorphism, Single NucleotidePyrethrinsRNA, ViralSequence Analysis, RNASpecies SpecificityThailandPyrethrinsRNA, Viral

Identifiers

PMID29549363
PMCPMC5856816
OpenAlexW2795250462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.