ArticleScientific reports2018
A proteomic insight into vitellogenesis during tick ovary maturation.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed.
- An insight into the ovary and midgut transcriptome of Dermacentor nitens tick.Ticks and tick-borne diseases · 2026Article
- Article
- Article
- Multi-Omics Technologies Applied to Improve Tick Research.Microorganisms · 2025Review
- Developmental Proteomics Reveals the Dynamic Expression Profile of Global Proteins ofLife (Basel, Switzerland) · 2025Article
- Article
- Morphological and Molecular Characterization of Tick Species Infesting Cattle in South Africa.Veterinary sciences · 2024Article
- Histopathological effects of the fruit extract of Citrullus colocynthis on the ovary of the tick Hyalomma dromedarii.Experimental & applied acarology · 2024Article
- Mining gene expression data for rational identification of novel drug targets and vaccine candidates against the cattle tick, Rhipicephalus microplus.Experimental & applied acarology · 2023Article
- Glucose metabolomic profile during embryogenesis in the tick Rhipicephalus microplus.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- Modulation of the PGEMolecules (Basel, Switzerland) · 2021Article
- Tick Ecdysteroid Hormone, Global Microbiota/Microorganisms · 2021Article
- The Ovarian Development Genes of Bisexual and ParthenogeneticFrontiers in veterinary science · 2021Article
- A physiologic overview of the organ-specific transcriptome of the cattle tick Rhipicephalus microplus.Scientific reports · 2020Article
- A proteomics analysis of the ovarian development in females of Haemaphysalis longicornis.Experimental & applied acarology · 2020Article
- Proteomic Analysis of Exosome-Like Vesicles Isolated From Saliva of the TickFrontiers in cellular and infection microbiology · 2020Article
- Ovary Proteome Analysis Reveals RH36 Regulates Reproduction via Vitellin Uptake Mediated by HSP70 Protein in Hard Ticks.Frontiers in cellular and infection microbiology · 2020Article
- Salivary gland proteome analysis of developing adult female Haemaphysalis longicornis ticks: molecular motor and TCA cycle-related proteins play an important role throughout development.Parasites & vectors · 2019Article
- Identification of proteins expressed by Babesia bigemina kinetes.Parasites & vectors · 2019Article
- Silencing expression of the Rhipicephalus microplus vitellogenin receptor gene blocks Babesia bovis transmission and interferes with oocyte maturation.Parasites & vectors · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Ticks are arthropod ectoparasites of importance for public and veterinary health. The understanding of tick oogenesis and embryogenesis could contribute to the development of novel control methods. However, to date, studies on the temporal dynamics of proteins during ovary development were not reported. In the present study we followed protein profile during ovary maturation. Proteomic analysis of ovary extracts was performed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) using shotgun strategy, in addition to dimethyl labelling-based protein quantification. A total of 3,756 proteins were identified, which were functionally annotated into 30 categories. Circa 80% of the annotated proteins belong to categories related to basal metabolism, such as protein synthesis and modification machineries, nuclear regulation, cytoskeleton, proteasome machinery, transcriptional machinery, energetic metabolism, extracellular matrix/cell adhesion, immunity, oxidation/detoxification metabolism, signal transduction, and storage. The abundance of selected proteins involved in yolk uptake and degradation, as well as vitellin accumulation during ovary maturation, was assessed using dimethyl-labelling quantification. In conclusion, proteins identified in this study provide a framework for future studies to elucidate tick development and validate candidate targets for novel control methods.
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Registered trials
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