ArticleScientific reports2018
Impact of human-associated Escherichia coli clonal groups in Antarctic pinnipeds: presence of ST73, ST95, ST141 and ST131.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 45 citations in OpenAlex.
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- One day in Denmark: whole-genome sequence-based analysis of Escherichia coli isolates from clinical settings.The Journal of antimicrobial chemotherapy · 2025Article
- Assessing the impact of sewage and wastewater on antimicrobial resistance in nearshore Antarctic biofilms and sediments.Environmental microbiome · 2025Article
- Diversity, distribution, and population structure of Escherichia coli in the lower gastrointestinal tract of humans.PloS one · 2025Article
- Emergence and Dissemination of Extraintestinal Pathogenic High-Risk International Clones ofLife (Basel, Switzerland) · 2022Review
- Longitudinal Study on Extended-Spectrum Beta-Lactamase-Microorganisms · 2022Article
- High Prevalence of Beta-Lactam-ResistantMicroorganisms · 2022Article
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- Characterization of beta-lactam-resistantMicrobial genomics · 2021Article
- The population genetics of pathogenic Escherichia coli.Nature reviews. Microbiology · 2021Review
- Escherichia coli Sequence Type 457 Is an Emerging Extended-Spectrum-β-Lactam-Resistant Lineage with Reservoirs in Wildlife and Food-Producing Animals.Antimicrobial agents and chemotherapy · 2020Article
- Distinguishing Pathovars from Nonpathovars: Escherichia coli.Microbiology spectrum · 2020Review
- Snapshot Study of Whole Genome Sequences ofAntibiotics (Basel, Switzerland) · 2020Article
- Genomic Characterization ofAntibiotics (Basel, Switzerland) · 2020Article
- Whole-Genome Sequencing-Based Characteristics in Extended-Spectrum Beta-Lactamase-ProducingMicroorganisms · 2020Article
- Whole Genome Sequencing and Characteristics ofFrontiers in microbiology · 2020Article
- Clonal ST131-Microbial genomics · 2019Article
- Association Between Kinetics of Early Biofilm Formation and Clonal Lineage inFrontiers in microbiology · 2019Article
- Swine Enteric Colibacillosis in Spain: Pathogenic Potential ofFrontiers in microbiology · 2018Article
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Authors and funding
13 authors at 5 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
There is growing concern about the spreading of human microorganisms in relatively untouched ecosystems such as the Antarctic region. For this reason, three pinniped species (Leptonychotes weddellii, Mirounga leonina and Arctocephalus gazella) from the west coast of the Antartic Peninsula were analysed for the presence of Escherichia spp. with the recovery of 158 E. coli and three E. albertii isolates. From those, 23 harboured different eae variants (α1, β1, β2, ε1, θ1, κ, ο), including a bfpA-positive isolate (O49:H10-A-ST206, eae-k) classified as typical enteropathogenic E. coli. Noteworthy, 62 of the 158 E. coli isolates (39.2%) exhibited the ExPEC status and 27 (17.1%) belonged to sequence types (ST) frequently occurring among urinary/bacteremia ExPEC clones: ST12, ST73, ST95, ST131 and ST141. We found similarities >85% within the PFGE-macrorrestriction profiles of pinniped and human clinic O2:H6-B2-ST141 and O16:H5/O25b:H4-B2-ST131 isolates. The in silico analysis of ST131 Cplx genomes from the three pinnipeds (five O25:H4-ST131/PST43-fimH22-virotype D; one O16:H5-ST131/PST506-fimH41; one O25:H4-ST6252/PST9-fimH22-virotype D1) identified IncF and IncI1 plasmids and revealed high core-genome similarities between pinniped and human isolates (H22 and H41 subclones). This is the first study to demonstrate the worrisome presence of human-associated E. coli clonal groups, including ST131, in Antarctic pinnipeds.
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