Evidence map›Paper›PMID 29549157›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2018

Molecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICA.

Thomas F Gamage, Charlotte E Farquhar, Timothy W Lefever, Julie A Marusich, Richard C Kevin, Iain S McGregor, Jenny L Wiley, Brian F Thomas

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Elucidating biased signaling in class A GPCRs.Trends in pharmacological sciences · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Cannabinoid 1 (CBBritish journal of pharmacology · 2023
    Article
  16. Article
  17. The endocannabinoid system and breathing.Frontiers in neuroscience · 2023
    Review
  18. Article
  19. Impact of ΔBiomedicines · 2022
    Article
  20. The Spicy Story of Cannabimimetic Indoles.Molecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Thomas F GamageRTI International, Research Triangle Park, North Carolina.ORCID 0000-0003-3528-9695
Charlotte E FarquharRTI International, Research Triangle Park, North Carolina.
Timothy W LefeverRTI International, Research Triangle Park, North Carolina.
Julie A MarusichRTI International, Research Triangle Park, North Carolina.
Richard C KevinThe University of Sydney, NSW, 2006, Australia.
Iain S McGregorThe University of Sydney, NSW, 2006, Australia.
Jenny L WileyRTI International, Research Triangle Park, North Carolina.
Brian F ThomasRTI International, Research Triangle Park, North Carolina; bft@rti.org.
RTI International · USThe University of Sydney · AU

Funding

THC RECEPTORSR01DA003672 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI WILEY, JENNY L. · 1985 to 2018
$4.9M
Investigation of Synthetic Cannabinoid Exposures and Pharmacological ConsequencesR01DA040460 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI RANGAN MAITRA, Yanan Zhang · 2016 to 2026
$4.5M
NIDA NIH HHS R01 DA003672NIDA NIH HHS R01 DA040460
6 · The paper itself

Abstract

Synthetic cannabinoids are a class of novel psychoactive substances that exhibit high affinity at the cannabinoid type-1 (CB

Indexed as

1-NaphthylamineAnimalsCannabinoidsCHO CellsCricetulusCyclic AMPHEK293 CellsHumansIllicit DrugsIndazolesMaleMiceMice, Inbred C57BLReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Signal Transduction1-NaphthylamineCannabinoidsCyclic AMPIllicit DrugsIndazolesmethyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoateN-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamideReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Valine

Identifiers

PMID29549157
PMCPMC5932312
OpenAlexW2794293351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.