Evidence map›Paper›PMID 29549122›Full record

ArticleThe Journal of biological chemistry2018

Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors.

Frans Vinberg, Igor V Peshenko, Jeannie Chen, Alexander M Dizhoor, Vladimir J Kefalov

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. The Journal of biological chemistry · 2020
    Article
  10. Article
  11. Calcium Sensors in Neuronal Function and Dysfunction.Cold Spring Harbor perspectives in biology · 2019
    Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Frans VinbergOphthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri 63110.
Igor V PeshenkoPennsylvania College of Optometry, Salus University, Elkins Park, Pennsylvania 19027.
Jeannie ChenZilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033.
Alexander M DizhoorPennsylvania College of Optometry, Salus University, Elkins Park, Pennsylvania 19027.
Vladimir J KefalovOphthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri 63110. Electronic address: kefalov@wustl.edu.
Salus University · USUniversity of Southern California · US

Funding

WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Philip Raymond Williams · 1985 to 2026
$18.4M
Phototransduction in health and diseaseR01EY012155 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jeannie Chen · 1998 to 2026
$11.8M
REGULATION OF CYCLIC GMP SYNTHESIS IN PHOTORECEPTORSR01EY011522 · NEI · WAYNE STATE UNIVERSITY · PI ALEXANDER M DIZHOOR · 1996 to 2026
$9.9M
MECHANISMS OF ADAPTATION IN MAMMALIAN CONESR01EY019312 · NEI · WASHINGTON UNIVERSITY · PI KEFALOV, VLADIMIR JIVKOV · 2009 to 2017
$3.3M
Analyses of retinal circuits after rod rescue in a mouse model of human blindnessR01EY027193 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, JEANNIE, FIELD, GREGORY DARIN · 2016 to 2020
$2.7M
PIGMENT DEPHOSPHORYLATION IN MAMMALIAN ROD AND CONE PHOTORECEPTORSR01EY025696 · NEI · WASHINGTON UNIVERSITY · PI KEFALOV, VLADIMIR JIVKOV · 2016 to 2019
$1.5M
CALCIUM HOMEOSTASIS IN MAMMALIAN ROD AND CONE PHOTORECEPTORSR01EY027387 · NEI · WASHINGTON UNIVERSITY · PI CHEN, JEANNIE, KEFALOV, VLADIMIR JIVKOV · 2017 to 2020
$1.4M
Assessment of Retinal Function in Health and Disease From Mouse To HumanR00EY026651 · NEI · UNIVERSITY OF UTAH · PI VINBERG, FRANS · 2017 to 2019
$722k
ASSESSMENT OF RETINAL FUNCTION IN HEALTH AND DISEASE FROM MOUSE TO HUMANK99EY026651 · NEI · WASHINGTON UNIVERSITY · PI VINBERG, FRANS · 2016 to 2017
$190k
NEI NIH HHS K99 EY026651NEI NIH HHS P30 EY002687NEI NIH HHS R00 EY026651NEI NIH HHS R01 EY011522NEI NIH HHS R01 EY012155NEI NIH HHS R01 EY019312NEI NIH HHS R01 EY025696NEI NIH HHS R01 EY027193NEI NIH HHS R01 EY027387
6 · The paper itself

Abstract

Light adaptation of photoreceptor cells is mediated by Ca

Indexed as

Adaptation, OcularAnimalsCalciumCyclic GMPGuanylate Cyclase-Activating ProteinsLight Signal TransductionMice, Inbred C57BLMice, KnockoutRetinal Cone Photoreceptor CellsSodium-Calcium ExchangerCalciumCyclic GMPGuanylate Cyclase-Activating ProteinsGuca1a protein, mouseGuca1b protein, mousepotassium-dependent sodium-calcium exchangerSodium-Calcium Exchangercalciumcolor visioncone photoreceptorguanylate cyclase activating proteinsguanylate cyclase (guanylyl cyclase)light activationlight adaptationphotoreceptorphotoresponsephototransductionretinavision

Identifiers

PMID29549122
PMCPMC5949989
OpenAlexW2792030698

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.