Evidence map›Paper›PMID 29548787›Full record

ArticlePreventive medicine2018

Inefficiencies of over-screening and under-screening for cervical cancer prevention in the U.S.

Philip E Castle, Cosette M Wheeler, Nicole G Campos, Stephen Sy, Emily A Burger, Jane J Kim, New Mexico HPV Pap Registry Steering Committee

Abstract read
In one paragraph

Article in Preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Philip E CastleDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address: philip.castle@einstein.yu.edu.
Cosette M WheelerDepartments of Pathology and Obstetrics and Gynecology, University of New Mexico, Albuquerque, NM, USA.
Nicole G CamposDepartment of Health Policy and Management, Harvard University, Boston, MA, USA.
Stephen SyDepartment of Health Policy and Management, Harvard University, Boston, MA, USA.
Emily A BurgerUniversity of Oslo, Oslo, Norway.
Jane J KimDepartment of Health Policy and Management, Harvard University, Boston, MA, USA.
New Mexico HPV Pap Registry Steering Committee
Harvard University · USAlbert Einstein College of Medicine · USUniversity of New Mexico · USUniversity of Oslo · NO

Funding

The EPI-STI Biostatistics and Bioinformatics Core (Cuzick/Wheeler)U19AI113187 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI WHEELER, COSETTE MARIE · 2014 to 2018
$12.6M
Patient- and Practice-Centered Assessment of Self-CollectionU54CA164336 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI WHEELER, COSETTE MARIE · 2011 to 2017
$5.5M
NCI NIH HHS U54 CA164336NIAID NIH HHS U19 AI113187
6 · The paper itself

Abstract

There is limited information on the cost-inefficiencies of non-adherence to recommended cervical cancer screening or the potential value for improving non-adherence. We estimated the incremental value of adhering to recommended screening every three years with cytology, using a disease simulation model that integrated real-world screening practice data from New Mexico. The amount that can be spent to improve adherence was estimated by calculating the incremental net monetary benefit (INMB) under scenarios of Current Practice (assuming a population of mixed adherence) and Uniformly Non-Adherent populations with imperfect or perfect adherence to follow-up of screen-positive women. Getting unscreened women screened every three years by cytology was a better value than increasing screening in the under-screened or reducing screening in the over-screened. For example, INMBs were $3998 for screening previously unscreened women versus $136 for eliminating annual screening at a willingness-to-pay threshold of $100,000 per quality-adjusted life-year gained. Strategies to reach unscreened women are potentially high-value investments.

Indexed as

Cost-Benefit AnalysisGuidelines as TopicAdultEarly Detection of CancerFemaleHumansMass ScreeningNew MexicoPapillomavirus InfectionsQuality-Adjusted Life YearsUnited StatesUterine Cervical Neoplasms

Identifiers

PMID29548787
PMCPMC5930058
OpenAlexW2789987113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.