Evidence map›Paper›PMID 29548689›Full record

ArticleAnnals of epidemiology2018

The association of cardiorespiratory fitness with cardiometabolic factors, markers of inflammation, and endothelial dysfunction in Latino youth: findings from the Hispanic Community Children's Health Study/Study of Latino Youth.

Carmen R Isasi, Garrett M Strizich, Robert Kaplan, Martha L Daviglus, Daniela Sotres-Alvarez, Denise C Vidot, Maria M Llabre, Gregory Talavera, Mercedes R Carnethon

Abstract readEvaluation Study
In one paragraph

Article in Annals of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Exercise Is a Vital Sign.HCA healthcare journal of medicine · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Carmen R IsasiDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY. Electronic address: carmen.isasi@einstein.yu.edu.
Garrett M StrizichDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY.
Robert KaplanDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY.
Martha L DaviglusInstitute for Minority Health Research, University of Illinois at Chicago, Chicago.
Daniela Sotres-AlvarezCollaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill.
Denise C VidotDepartment of Psychology, University of Miami Miller School of Medicine, Miami, FL.
Maria M LlabreDepartment of Psychology, University of Miami, Miami, FL.
Gregory TalaveraInstitute for Behavioral and Community Health, Graduate School of Public Health, San Diego State University, San Diego, CA.
Mercedes R CarnethonDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Albert Einstein College of Medicine · USUniversity of Miami · USNorthwestern University · USSan Diego State University · USUniversity of Illinois Chicago · USUniversity of North Carolina at Chapel Hill · US

Funding

Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI Ronald T. Ackermann, MARSHALL H CHIN · 2011 to 2026
$10.0M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Hispanic Community Children???s Health Study of Latino Youth SOL-YouthR01HL102130 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AYALA, GUADALUPE X, BANGDIWALA, SHRIKANT I · 2011 to 2014
$7.5M
Cardiometabolic Outcomes in Multi-ethnic Physical Activity & Sedentary Behavior Study (COMPASS)R01HL136266 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KAPLAN, ROBERT C, MOSSAVAR-RAHMANI, YASMIN · 2017 to 2020
$3.1M
Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
GENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7M
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NCATS NIH HHS UL1 TR001073NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS R01 HL102130NHLBI NIH HHS R01 HL136266NIDDK NIH HHS P30 DK092949NIDDK NIH HHS P30 DK111022
6 · The paper itself

Abstract

purposeTo evaluate the relationship of cardiorespiratory fitness (CRF) with cardiovascular disease risk factors and a biomarker of endothelial dysfunction (e-selectin) among Hispanic/Latino youth.

methodsThe study included 1380 Hispanic/Latino youths (8-16 years old) from the Hispanic Community Children's Health Study/Study of Latino Youth that enrolled from four cities (Bronx, Chicago, Miami, and San Diego). CRF was assessed by a 3-minute step test that uses postexercise heart rate to estimate maximal oxygen uptake. Regression models assessed differences in cardiometabolic markers across quartiles of CRF, adjusting for potential confounders.

resultsCRF was higher among boys (mean: 57.6 mL per kg/min, 95% confidence interval, 56.8-58.4) compared to girls (mean: 54.7 mL per kg/min, 95% confidence interval, 53.9-55.5). Higher levels of CRF were associated with more favorable levels of cardiometabolic, inflammation, and endothelial dysfunction factors (P-values <.001) and independently of physical activity and sedentary time. Compared to the lowest quartile of CRF, the odds of having greater than or equal to two cardiovascular disease risk factors was lower at higher quartiles of CRF, after adjustment for potential confounders.

conclusionsAmong Hispanic/Latino youth, CRF appears to be a strong protective factor for endothelial dysfunction and cardiometabolic risk factors. Strategies to improve CRF may be a useful approach for improving cardiovascular health in youth.

Indexed as

AdolescentCardiorespiratory FitnessCardiovascular DiseasesChildChild HealthExerciseFemaleHealth SurveysHeart RateHispanic or LatinoHumansMaleMetabolic DiseasesObesityPhysical FitnessUnited StatesCardiometabolic riskCardiorrespiratory fitnessChildrenEndothelial functionHispanic

Identifiers

PMID29548689
PMCPMC6093801
OpenAlexW2791950071

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.