Evidence map›Paper›PMID 29548319›Full record

ArticleBMC urology2018

Fungaemia caused by obstructive renal candida bezoars leads to bilateral chorioretinitis: a case report.

Johannes Stein, Stefan Latz, Jörg Ellinger, Guido Fechner, Maher Safi, Philipp Krausewitz, Simone Müller, Karin Weyer, Stefan C Müller

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Diabetic ketoacidosis fromAcute medicine & surgery
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Johannes SteinDepartment of Urology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany. Johannes.stein@ukb.uni-bonn.de.ORCID http://orcid.org/0000-0002-6316-1229
Stefan LatzDepartment of Urology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
Jörg EllingerDepartment of Urology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
Guido FechnerDepartment of Urology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
Maher SafiDepartment of Urology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
Philipp KrausewitzDepartment of Urology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
Simone MüllerDepartment of Ophthalmology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
Karin WeyerDepartment of Urology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
Stefan C MüllerDepartment of Urology, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
University of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal fungal bezoars are remarkably rare and mostly occur in immunodeficient patients. Only a small number of cases with immunocompetent patients have been published so far. The published treatment approaches comprised systemic antimycotic therapy and surgical or minimal invasive removal of the fungal balls. In some cases irrigation of the renal duct system with amphotericin B was performed. By obstruction of the urinary tract bezoars can lead to infected hydronephrosis and severe urosepsis with high lethality. Fungaemia can cause fungal colonization in different distant organs. Fulminant chorioretinitis and irreversible visual impairment can be the consequence of ocular fundus colonization. The following report highlights that a co-operation between urologists and ophthalmologists is absolutely indispensible in case of fungaemia. CASE PRESENTATION: Hereinafter we describe a case of an immunocompetent 56 years old woman, presenting with flank pain and shivering. The diagnosis turned out to be difficult due to initially negative urine culture. The fungaemia caused by obstructive nephropathy led to bilateral candida chorioretinitis. The patient was treated with intravenous amphotericin b and the bezoar was removed by percutaneous "nephrolitholapaxy". After two months, a follow up revealed the patient felt well, chorioretinal lesions regressed and urine culture did not show any fungal growth.

conclusionTo the best of our knowledge, this is the first case reporting on obstructive renal bezoars, which lead to haematogenous fungus spread and bilateral chorioretinitis. It points out that extensive ophthalmologic examination should be performed in case of fungaemia even if the patient is not suffering from any visual impairment.

Indexed as

Antifungal AgentsBezoarsCandidiasisChorioretinitisCombined Modality TherapyFemaleFungemiaHumansKidney DiseasesMiddle AgedNephrolithotomy, PercutaneousAntifungal AgentsCandida chorioretinitisCandida glabrataFungaemiaObstructive nephropathyRenal bezoars

Identifiers

PMID29548319
PMCPMC5857136
OpenAlexW2802305105

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.