ArticleMolecules (Basel, Switzerland)2018
Antiviral Activity of Novel Quinoline Derivatives against Dengue Virus Serotype 2.
Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed, 91 citations in OpenAlex.
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- 2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives.Molecules (Basel, Switzerland) · 2024Review
- Synthesis and biological activity of imidazole phenazine derivatives as potential inhibitors for NS2B-NS3 dengue protease.Heliyon · 2024Article
- Design, Synthesis and Antitumor Activity of Quercetin Derivatives Containing a Quinoline Moiety.Molecules (Basel, Switzerland) · 2024Article
- Indol-3-ylglyoxylamide as Privileged Scaffold in Medicinal Chemistry.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Molluscicidal and Larvicidal Potency ofPharmaceutics · 2023Article
- Synthesis of 2-(6-substituted quinolin-4-yl)-1-alkoxypropan-2-ol as potential antimycobacterial agents.Chemicke zvesti · 2023Article
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- Novel 4-Azapregnene Derivatives as Potential Anticancer Agents: Synthesis, Antiproliferative Activity and Molecular Docking Studies.Molecules (Basel, Switzerland) · 2022Article
- Glycyrrhizic Acid Derivatives Bearing Amino Acid Residues in the Carbohydrate Part as Dengue Virus E Protein Inhibitors: Synthesis and Antiviral Activity.International journal of molecular sciences · 2022Article
- Electrospun Polymer Materials with Fungicidal Activity: A Review.Molecules (Basel, Switzerland) · 2022Review
- Synthesis of new series of quinoline derivatives with insecticidal effects on larval vectors of malaria and dengue diseases.Scientific reports · 2022Article
- Article
- Synthesis, delivery, and molecular docking of fused quinolines as inhibitor of Hepatitis A virus 3C proteinase.Scientific reports · 2021Article
- Biological activity and molecular docking studies of some new quinolines as potent anticancer agents.Medical oncology (Northwood, London, England) · 2021Article
- 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol as potential antiviral SARS-CoV-2 candidate: Synthesis, crystal structure, Hirshfeld surface analysis, DFT and molecular docking studies.Journal of molecular structure · 2021Article
- Synthetic and medicinal perspective of quinolines as antiviral agents.European journal of medicinal chemistry · 2021Review
- Development of an efficient, one-pot, multicomponent protocol for synthesis of 8-hydroxy-4-phenyl-1,2-dihydroquinoline derivatives.Journal of heterocyclic chemistry · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
Dengue virus causes dengue fever, a debilitating disease with an increasing incidence in many tropical and subtropical territories. So far, there are no effective antivirals licensed to treat this virus. Here we describe the synthesis and antiviral activity evaluation of two compounds based on the quinoline scaffold, which has shown potential for the development of molecules with various biological activities. Two of the tested compounds showed dose-dependent inhibition of dengue virus serotype 2 in the low and sub micromolar range. The compounds
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.