ArticleAIDS (London, England)2018
Multitype violence exposures and adolescent antiretroviral nonadherence in South Africa.
Article in AIDS (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07132905 (Randomized Pilot Trial of Church-Based Problem-Solving Therapy for Adolescent Girls and Young Women With a History of Gender-Based Violence in Zambia), which is not on this map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Pilot Trial of Church-Based Problem-Solving Therapy for Adolescent Girls and Young Women With a History of Gender-Based Violence in Zambia
Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Prevalence of physical and sexual violence and psychological abuse among adolescents and young adults living with HIV in Zambia.PloS one · 2020Trial
- Article
- Needs Assessment to Inform a Life Course-Based Support Programme for Adolescents with Perinatally Acquired HIV in Rural Limpopo, South Africa.International journal of environmental research and public health · 2026Article
- Factors associated with antiretroviral therapy adherence among adolescents living with HIV in Addis Ababa, Ethiopia: structural equation modeling.AIDS research and therapy · 2026Article
- Health services' responses to transitioning adolescents to adult HIV care in South Africa.African journal of primary health care & family medicine · 2025Article
- "I-We-I": Visualizing Adolescents' Perceptions and Apprehension to Transition to Adult HIV Care at a Supportive Transition Facility in the Cape Town Metropole, South Africa.Tropical medicine and infectious disease · 2025Article
- Violence as an obstacle to HIV medication adherence and viral suppression: A daily diary investigation among adolescent boys.Social science & medicine (1982) · 2025Article
- Toward a Contextually Sensitive Understanding of Polyvictimization: A Latent Class Analysis of Violence, Risks, and Protections Among South African Adolescents From Highly Deprived Settings.Journal of interpersonal violence · 2024Article
- Can Support Groups Improve Treatment Adherence and Reduce Sexual Risk Behavior among Young People Living with HIV? Results from a Cohort Study in South Africa.Tropical medicine and infectious disease · 2024Article
- Pathways between adverse childhood experiences and viral suppression among male HIV-infected adolescents in South Africa.AIDS care · 2024Article
- Social Determinants of Adherence to Treatment for Tuberculosis Infection and Disease Among Children, Adolescents, and Young Adults: A Narrative Review.Journal of the Pediatric Infectious Diseases Society · 2022Review
- 'So hurt and broken': A qualitative study of experiences of violence and HIV outcomes among Zambian youth living with HIV.Global public health · 2022Article
- Nonsexual violence against children and adolescents: a study in a Latin American tertiary and university hospital.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2022Article
- Teacher violence from the perspectives of teachers and students and related factors: A survey in Southern Iran.Frontiers in psychology · 2022Article
- 'You just prefer to die early!': how socioecological context impedes treatment for people living with HIV in Iran.BMJ global health · 2021Article
- Experiences with a violence and mental health safety protocol for a randomized controlled trial to support youth living with HIV.Global health research and policy · 2021Article
- Clinic and care: associations with adolescent antiretroviral therapy adherence in a prospective cohort in South Africa.AIDS (London, England) · 2021Article
- Past-Year Violence Victimization is Associated with Viral Load Failure Among HIV-Positive Adolescents and Young Adults.AIDS and behavior · 2021Article
- Childhood trauma, major depressive disorder, suicidality, and the modifying role of social support among adolescents living with HIV in rural Uganda.Journal of affective disorders reports · 2021Article
- "We need our own clinics": Adolescents' living with HIV recommendations for a responsive health system.PloS one · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
objectivesHIV-positive adolescents have low-ART adherence, with consequent increased risks of mortality, morbidity, and viral resistance. Despite high rates of violence against children in the Africa region, no known studies have tested impacts on HIV-positive adolescents. We examine associations of ART adherence with adolescent violence victimization by caregivers, teachers, peers, community members, and healthcare providers. DESIGN AND
methodsHIV-positive adolescents were interviewed (n = 1060), and clinic biomarker data collected. We sampled all 10-19-year olds ever ART-initiated within 53 clinics in 180 South African communities (90.1% reached). Analyses examined associations between nonadherence and nine violence types using sequential multivariate logistic regressions. Interactive and additive effects were tested with regression and marginal effects.
resultsPast-week self-reported ART nonadherence was 36%. Nonadherence correlated strongly with virologic failure (OR 2.3, CI 1.4-3.8) and symptomatic pulmonary tuberculosis (OR 1.49, CI 1.18-2.05). Four violence types were independently associated with nonadherence: physical abuse by caregivers (OR 1.5, CI 1.1-2.1); witnessing domestic violence (OR 1.8, CI 1.22-2.66); teacher violence (OR 1.51, CI 1.16-1.96,) and verbal victimization by healthcare staff (OR 2.15, CI 1.59-2.93). Past-week nonadherence rose from 25% with no violence to 73.5% with four types of violence exposure.
conclusionViolence exposures at home, school, and clinic are major and cumulating risks for adolescent antiretroviral nonadherence. Prevention, mitigation, and protection services may be essential for the health and survival of HIV-positive adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.