Evidence map›Paper›PMID 29547266›Full record

ArticleBiochemistry2018

Dynamic Characteristics of Guanosine-5'-monophosphate Reductase Complexes Revealed by High-Resolution

Masha M Rosenberg, Alfred G Redfield, Mary F Roberts, Lizbeth Hedstrom

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. High ResolutionFrontiers in molecular biosciences · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Masha M RosenbergDepartment of Biology , Brandeis University , MS009, 415 South Street , Waltham , Massachusetts 02453-9110 , United States.
Alfred G RedfieldDepartment of Biochemistry , Brandeis University , MS009, 415 South Street , Waltham , Massachusetts 02453-9110 , United States.
Mary F RobertsDepartment of Chemistry , Boston College , 140 Commonwealth Avenue , Chestnut Hill , Massachusetts 02467-9110 , United States.
Lizbeth HedstromDepartment of Biology , Brandeis University , MS009, 415 South Street , Waltham , Massachusetts 02453-9110 , United States.
Brandeis University · USBoston College · US

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
INOSINE MONOPHOSPHATE DEHYDROGENASER01GM054403 · NIGMS · BRANDEIS UNIVERSITY · PI HEDSTROM, LIZBETH K. · 1998 to 2016
$4.2M
NIGMS NIH HHS P41 GM103311NIGMS NIH HHS R01 GM054403
6 · The paper itself

Abstract

The ability of enzymes to modulate the dynamics of bound substrates and cofactors is a critical feature of catalysis, but the role of dynamics has largely been approached from the perspective of the protein. Here, we use an underappreciated NMR technique, subtesla high-resolution field-cycling

Indexed as

Binding SitesCatalysisGMP ReductaseGuanosineKineticsMagnetic Resonance ImagingMagnetic Resonance SpectroscopyModels, MolecularNADPProtein BindingGMP ReductaseGuanosineNADP

Identifiers

PMID29547266
PMCPMC6467290
OpenAlexW2792650885

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.