Evidence map›Paper›PMID 29547009›Full record

ArticleAmerican journal of respiratory and critical care medicine2018

Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial Hypertension Revealed by Induced Pluripotent Stem Cell Modeling.

Fedir N Kiskin, C-Hong Chang, Christopher J Z Huang, Baraa Kwieder, Christine Cheung, Benjamin J Dunmore, Felipe Serrano, Sanjay Sinha, Nicholas W Morrell, Amer A Rana

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Use of iPSC-Derived Smooth Muscle Cells to Model Physiology and Pathology.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Human pluripotent stem cells for the modelling and treatment of respiratory diseases.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. The P2-receptor-mediated CaPurinergic signalling · 2019
    Article
  13. Genetics and genomics of pulmonary arterial hypertension.The European respiratory journal · 2019
    Review
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Fedir N Kiskin1 University of Cambridge Cambridge, United Kingdom.ORCID 0000-0002-6984-9622
C-Hong Chang1 University of Cambridge Cambridge, United Kingdom.
Christopher J Z Huang1 University of Cambridge Cambridge, United Kingdom.
Baraa Kwieder1 University of Cambridge Cambridge, United Kingdom.
Christine Cheung3 Nanyang Technological University Singapore.
Benjamin J Dunmore1 University of Cambridge Cambridge, United Kingdom.
Felipe Serrano1 University of Cambridge Cambridge, United Kingdom.
Sanjay Sinha1 University of Cambridge Cambridge, United Kingdom.
Nicholas W Morrell1 University of Cambridge Cambridge, United Kingdom.
Amer A Rana1 University of Cambridge Cambridge, United Kingdom.ORCID 0000-0002-2330-4643
University of Cambridge · GBNanyang Technological University · SGWellcome/MRC Cambridge Stem Cell Institute · GB

Funding

British Heart Foundation CH/09/001/25945British Heart Foundation FS/13/29/30024British Heart Foundation FS/13/51/30636British Heart Foundation FS/18/46/33663British Heart Foundation PG/14/31/30786British Heart Foundation RE/13/6/30180British Heart Foundation RG/13/4/30107British Heart Foundation RG/17/5/32936British Heart Foundation RM/13/3/30159British Heart Foundation SP/12/12/29836Department of HealthMedical Research Council MC_PC_12009Medical Research Council MR/K020919/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Induced Pluripotent Stem CellsMutationPhenotypeAdultAgedAged, 80 and overBone Morphogenetic Protein Receptors, Type IIFamilial Primary Pulmonary HypertensionFemaleHumansMaleMiddle AgedBone Morphogenetic Protein Receptors, Type II

Identifiers

PMID29547009
PMCPMC6058985
OpenAlexW2789293026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.