Evidence map›Paper›PMID 29546729›Full record

Observational studyClinical cardiology2018

Stroke-prevention strategies in North American patients with atrial fibrillation: The GLORIA-AF registry program.

William F McIntyre, David Conen, Brian Olshansky, Jonathan L Halperin, Emil Hayek, Menno V Huisman, Gregory Y H Lip, Shihai Lu, Jeff S Healey

Open access · hybridAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 8 countries.

William F McIntyreDepartment of Medicine, Division of Cardiology, McMaster University, Hamilton, Ontario, Canada.ORCID http://orcid.org/0000-0001-6082-7542
David ConenDepartment of Medicine, Division of Cardiology, McMaster University, Hamilton, Ontario, Canada.
Brian OlshanskyMercy Heart & Vascular Institute, Mason City, Iowa.
Jonathan L HalperinThe Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.
Emil HayekDepartment of Cardiology, University Hospitals of Cleveland, Cleveland, Ohio.
Menno V HuismanDepartment of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, Netherlands.
Gregory Y H LipInstitute of Cardiovascular Sciences, University of Birmingham, United Kingdom, and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Shihai LuDepartment of Biostatistics, Boehringer Ingelheim, Ridgefield, Connecticut.
Jeff S HealeyDepartment of Medicine, Division of Cardiology, McMaster University, Hamilton, Ontario, Canada.
McMaster University · CABoehringer Ingelheim (Brazil) · BRLeiden University Medical Center · NLMercy Medical Center · USMount Sinai Medical Center · USUniversity Hospital of Basel · CHUniversity Hospitals of Cleveland · USUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntithrombotic prophylaxis with oral anticoagulation (OAC) substantially reduces stroke and mortality in patients with atrial fibrillation (AF). HYPOTHESIS: Analysis of data in the Global Registry on Long-Term Antithrombotic Treatments in Patients With Atrial Fibrillation (GLORIA-AF), an international, observational registry of patients with newly diagnosed AF, can identify factors associated with treatment decisions and outcomes.

methodsMultivariable regression identified patient, physician, and temporal factors associated with OAC prescription, compared with management with antiplatelet drugs or no antithrombotic drugs in North American patients enrolled between November 2011 and February 2014.

resultsOf 3320 eligible patients (mean age, 71 ± 11 years; 1879 males with CHA

conclusionsIn GLORIA-AF, 20% of the population comprising males with CHA

Indexed as

Accidental FallsAdministration, OralAgedAged, 80 and overAnticoagulantsAtrial FibrillationClinical Decision-MakingFemaleFibrinolytic AgentsHemorrhageHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisNorth AmericaAnticoagulantsFibrinolytic AgentsPlatelet Aggregation InhibitorsAtrial FibrillationOral AnticoagulationStroke

Identifiers

PMID29546729
PMCPMC6032943
OpenAlexW2792765218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.