ReviewMusculoskeletal surgery2018
Manipulation under anesthesia following total knee arthroplasty: a comprehensive review of literature.
Review in Musculoskeletal surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Time-sensitive ambulatory orthopaedic soft-tissue surgery paradigms during the COVID-19 pandemic.International orthopaedics · 2020Pooled it
- Chronic Pain and Stiffness After Total Knee Arthroplasty: A Comprehensive, Phenotype-Based Review of Mechanisms, Diagnosis and Management.Journal of clinical medicine · 2026Review
- Post-operative joint stiffness after Bereiter trochleoplasty does not affect 2-year improvement in patient-reported outcomes. A prospective cohort study of 374 Bereiter trochleoplasties.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Day case hip and knee replacement in England: a population-based cohort study using linked National Joint Registry and Hospital Episode Statistics data.BMC medicine · 2025Article
- [Postoperative rehabilitation after knee arthroplasty].Orthopadie (Heidelberg, Germany) · 2024Review
- Postoperative Continuous Passive Motion Does Not Improve the Range of Movement Achieved After Manipulation Under Anesthetic for Stiffness in Total Knee Replacement.Arthroplasty today · 2024Article
- Management of fixed flexion contracture in primary total knee arthroplasty: recent systematic review.SICOT-J · 2024Article
- Article
- Increased rate of complications following total knee arthroplasty in patients with systemic sclerosis.International orthopaedics · 2023Article
- No component loosening of a cementless deep dish rotating platform knee at a 5-year follow-up.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Observational
- Immune cell populations differ in patients undergoing revision total knee arthroplasty for arthrofibrosis.Scientific reports · 2022Article
- Acute Femoropopliteal Bypass Graft Occlusion After Knee Manipulation Under Anesthesia: A Case Report and Review of Current Literature.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022Article
- Management of Stiffness following Total Knee Arthroplasty: International Survey on Surgeon Preferences.SICOT-J · 2021Article
- Recovery of knee range of motion after total knee arthroplasty in the first postoperative weeks: poor recovery can be detected early.Musculoskeletal surgery · 2019Article
- The stiff total knee arthroplasty: causes, treatment modalities and results.EFORT open reviews · 2019Review
- Manipulation under anesthesia after primary knee arthroplasty in Sweden: incidence, patient characteristics and risk of revision.Acta orthopaedica · 2019Article
- [Open arthrolysis for stiff knee after primary total knee arthroplasty].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe etiology of the stiff knee after total knee arthroplasty (TKA) is largely unknown, although excessive scar tissue due to arthrofibrosis is an important reason for a limited range of motion (ROM) after this procedure. Persistent limited ROM after TKA results in poor patient-reported outcomes and is increasingly becoming a more prominent reason for TKA revision surgery.
methodsA narrative review of current literature on manipulation under anesthesia (MUA) after TKA analyzing etiology and risk factors for stiffness after TKA, effectiveness of MUA and what is known about rehabilitation after MUA.
resultsLiterature describes numerous risk factors for insufficient knee ROM after TKA, but a comprehensive valid risk model is lacking. MUA is an effective treatment option with evidence suggesting better outcomes if performed within the first 3 months after TKA. The wide variety in both the indication and timing for MUA, and the lack of scientific evidence on how to rehabilitate patients after MUA, complicates the interpretation of available literature. This is even more so the case on the reporting of one versus two or more MUAs after TKA.
conclusionFuture comparative trials, preferably with a randomized study design, should be conducted to elude more clear indications for MUA, to give clinical guidance on correct timing for MUA and on how to rehabilitate patients afterward.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.