Evidence map›Paper›PMID 29546641›Full record

SynthesisSports medicine (Auckland, N.Z.)2018

The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance in Humans: A Meta-Analysis.

Mark Waldron, Stephen David Patterson, Jamie Tallent, Owen Jeffries

Registry-linked trialAbstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07654946 (Near-Infrared Spectroscopy-Derived Mitochondrial Oxidative Phosphorylation Capacity, Local Muscular Fatigue Resistance, and the Effects of Acute Taurine Supplementation), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07654946 narecruitingnot on this mapstarted 2026, after this paper: background citation

Near-Infrared Spectroscopy-Derived Mitochondrial Oxidative Phosphorylation Capacity, Local Muscular Fatigue Resistance, and the Effects of Acute Taurine Supplementation

TypeinterventionalSponsorLouisiana State University and A&M CollegeRan2026 to 2027Enrolled34ConditionsLocal Muscular Endurance and Fatigue, NIRS Skeletal Muscle Mitochondrial Capacity, Acute Taurine SupplementationArmsAcute Taurine Supplementation, Acute Placebo Supplementation
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  18. A PTER-dependent pathway of taurine metabolism linked to energy balance.bioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mark WaldronSchool of Health, Sport and Applied Sciences, St Mary's University, London, TW1 4SX, UK. mark.waldron@stmarys.ac.uk.
Stephen David PattersonSchool of Health, Sport and Applied Sciences, St Mary's University, London, TW1 4SX, UK.
Jamie TallentSchool of Health, Sport and Applied Sciences, St Mary's University, London, TW1 4SX, UK.
Owen JeffriesSchool of Health, Sport and Applied Sciences, St Mary's University, London, TW1 4SX, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTaurine is central to many physiological processes, some of which are augmented by exogenous supply and have the potential to facilitate endurance performance; however, its independent effects on performance have not been systematically analysed.

objectiveTo evaluate the effects of isolated oral taurine ingestion on endurance performance and to assess the contribution of (1) the dose and (2) the supplementation period to the ergogenic effect.

methodsA search was performed using various databases in September 2017. The studies were screened using search criteria for eligibility. Ten peer-reviewed articles were identified for inclusion. A sub-analysis of time-to-exhaustion (TTE) trials (n = 7) was also performed. The effects of (1) dose and (2) the acute (single dose) or chronic (> 1 day) supplementation periods were assessed using meta-regression. The doses of taurine ranged from 1 to 6 g/day and were provided in single doses and for up to 2 weeks among a range of subjects.

resultsTaurine ingestion improved overall endurance performance (Hedges' g = 0.40, 95% CI 0.12-0.67, P = 0.004), which was similar in TTE trials (Hedges' g = 0.43, 95% CI 0.12-0.75, P = 0.007). There were no differences between acute or chronic supplementation for the full sample (P = 0.897) or the TTE group (P = 0.896). The dose of taurine did not moderate its effect on endurance performance (P > 0.05).

conclusionHuman endurance performance can be improved by orally ingesting a single dose of taurine in varying amounts (1-6 g).

Indexed as

Athletic PerformanceDietary SupplementsEnergy MetabolismExerciseFemaleHumansMaleOxygen ConsumptionPhysical EnduranceTaurineTaurine

Identifiers

PMID29546641

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.