Evidence map›Paper›PMID 29546569›Full record

ArticleClinical journal of gastroenterology2018

A case of duodenal malignant lymphoma presenting as acute pancreatitis: systemic lupus erythematosus and immunosuppressive therapy as risk factors.

Reiko Yamada, Takashi Sakuno, Hiroyuki Inoue, Hiroshi Miura, Toshifumi Takeuchi, Yasunori Shiono, Hiroaki Okuse, Misaki Nakamura, Masaki Katsurahara, Yasuhiko Hamada and 3 more

Abstract readCase Reports
In one paragraph

Article in Clinical journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Reiko YamadaDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. reiko-t@clin.medic.mie-u.ac.jp.
Takashi SakunoDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Hiroyuki InoueDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Hiroshi MiuraDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Toshifumi TakeuchiDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Yasunori ShionoDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Hiroaki OkuseDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Misaki NakamuraDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Masaki KatsuraharaDepartment of Endoscopy, Mie University Graduate School of Medicine, Tsu, Japan.
Yasuhiko HamadaDepartment of Endoscopy, Mie University Graduate School of Medicine, Tsu, Japan.
Kyosuke TanakaDepartment of Endoscopy, Mie University Graduate School of Medicine, Tsu, Japan.
Noriyuki HorikiDepartment of Endoscopy, Mie University Graduate School of Medicine, Tsu, Japan.
Yoshiyuki TakeiDepartment of Gastroenterology and Hepatology, Mie University Hospital, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 49-year-old man was admitted to our hospital with pancreatitis. He was diagnosed with systemic lupus erythematosus at 34 years of age and was being treated with oral tacrolimus (3 mg/day) and predonine (10 mg/day) for the past 15 months. The computed tomography (CT) scan showed the mass lesion had invaded the pancreatic head via thickening of the duodenal wall. Upper gastrointestinal endoscopy showed the all-round ulcerative lesion from the superior duodenal angle to the descending portion. Histological examination confirmed the diagnosis of diffuse large B cell lymphoma (DLBCL). Tacrolimus therapy was stopped due to the possibility of immunodeficiency-related lymphoproliferative disease; however, the lesion did not improve. Consequently, he was administered rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). After six courses of R-CHOP therapy, a partial response was confirmed on CT. One month after the completion of chemotherapy, a gastrojejunal anastomosis was performed because of duodenal stenosis. He has since been well without recurrence. It was difficult to identify the risk factor for DLBCL; therefore, both the disease activity and immunosuppressive therapy should be taken into consideration as carrying a risk. In the present case, the symptom of pancreatitis enabled an early diagnosis of DLBCL.

Indexed as

Acute DiseaseAntibodies, Monoclonal, Murine-DerivedAnti-Inflammatory AgentsAntineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDoxorubicinDuodenal NeoplasmsHumansImmunosuppressive AgentsLupus Erythematosus, SystemicLymphoma, Large B-Cell, DiffuseMaleMiddle AgedPancreatitisPrednisolonePrednisoneAntibodies, Monoclonal, Murine-DerivedAnti-Inflammatory AgentsCyclophosphamideDoxorubicinImmunosuppressive AgentsPrednisolonePrednisoneR-CHOP protocolRituximabTacrolimusVincristineDuodenal malignant lymphomaImmunosuppressive therapy-associated lymphoproliferative disordersPancreatitisSystemic lupus erythematosus (SLE)Tacrolimus

Identifiers

PMID29546569
PMCPMC6096942

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.