ArticleInternational journal of colorectal disease2018
The effect of marital status by age on patients with colorectal cancer over the past decades: a SEER-based analysis.
Article in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mortality rate and predictors of colorectal cancer patients in Ethiopia: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Marital Status, Living Arrangement, and Cancer Recurrence and Survival in Patients with Stage III Colon Cancer: Findings from CALGB 89803 (Alliance).The oncologist · 2022Trial
- Exploring the role of marital status on survival and stage at diagnosis in early-onset colorectal cancer by race/ethnicity.Scientific reports · 2026Article
- The Molecular Signature of Early-Onset Colorectal Cancer Liver Metastases: Distinct Biology and Clinical Challenges.International journal of molecular sciences · 2026Review
- Prognostic model for early-onset colorectal cancer with liver metastasis after primary tumor resection and chemotherapy.Scientific reports · 2025Article
- Survival Outcomes of U.S. Patients with CMML: A Two-Decade Analysis from the SEER Database.Medical sciences (Basel, Switzerland) · 2024Article
- Outcomes of Patients with Gastrointestinal Stromal Tumors in the Past Decade.Medical sciences (Basel, Switzerland) · 2023Article
- Article
- Primary Cardiac Sarcoma: Clinical Characteristics and Prognostic Factors over the Past 2 Decades.Diseases (Basel, Switzerland) · 2023Article
- Interaction between Age and Primary Site on Survival Outcomes in Primary GI Melanoma over the Past Decade.Medical sciences (Basel, Switzerland) · 2023Article
- Interaction between age and gender on survival outcomes in extramedullary multiple myeloma over the past two decades.World journal of clinical oncology · 2023Article
- Hormone replacement therapy in relation to the risk of colorectal cancer in women by BMI: a multicentre study with propensity score matching.International journal of clinical oncology · 2022Article
- Observational
- Surgical Methods and Social Factors Are Associated With Long-Term Survival in Follicular Thyroid Carcinoma: Construction and Validation of a Prognostic Model Based on Machine Learning Algorithms.Frontiers in oncology · 2022Article
- The effect of marital status on stage at diagnosis and survival in Saudis diagnosed with colorectal cancer: cancer registry analysis.Scientific reports · 2021Article
- Marital status and survival of patients with colorectal signet ring cell carcinoma: a population-based study.Scientific reports · 2020Article
- Influence of marital status on overall survival in adult patients with chordoma: a SEER-based study.Journal of orthopaedic surgery and research · 2020Article
- Clinicopathological characteristics and prediction of cancer-specific survival in large cell lung cancer: a population-based study.Journal of thoracic disease · 2020Article
- Influence of marital status on overall survival in patients with ovarian serous carcinoma: finding from the surveillance epidemiology and end results (SEER) database.Journal of ovarian research · 2019Article
- The impact of marital status on survival in patients with surgically treated colon cancer.Medicine · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMarital status has been found as an independent prognostic factor for survival in colorectal cancer (CRC). However, it is unclear whether patients with different marital status have benefited the same from the treatment improvement.
methodsWe queried the Surveillance, Epidemiology, and End Results (SEER) 9 database for patients diagnosed with CRC from 1975 to 2009. Yearly survival data was presented with overlying loess smoothing lines, stratifying by marital status. We further referred to the SEER 18 database for patients diagnosed with CRC from 1973 to 2014. We also performed yearly data for stage proportion, surgery-performed rate, cancer-specific survival (CSS), and multivariate hazard ratio with overlying loess smoothing lines across all marital status.
resultsFive-year CSS of married, single, and separated/divorced patients showed remarkable increase since 1975; however, survival of widowed patients remained low and no survival gains were observed since 1990. The same trends persisted after stratifying patients by stage and gender. Married and widowed patients tended to have more localized disease and less distant disease compared with the other two groups, and married patients were more likely to receive surgery. Multivariate analysis revealed the hazard ratio of widowed patients dropped dramatically when including age at diagnosis.
conclusionsWidowed patients have not benefited substantially from the remarkable treatment improvement over the past four decades, which may be the result of the older age of this particular group. This study is a wake-up call to the medical community for additional care for the widowed patients.
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