ReviewCurrent treatment options in oncology2018
Epithelioid Hemangioendothelioma: Update on Diagnosis and Treatment.
Review in Current treatment options in oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
81 citing papers in PubMed, 152 citations in OpenAlex.
- Hemoptysis in a 48-Year-Old Man.CHEST pulmonary · 2026Article
- Characteristics of patients with epithelioid hemangioendothelioma (EHE): a retrospective analysis of the Charité- Universitätsmedizin Berlin.Journal of cancer research and clinical oncology · 2026Article
- Epithelioid hemangioendothelioma presenting as multiple pulmonary nodules following primary lung adenocarcinoma resection: a diagnostic challenge and clinical management dilemma.Journal of surgical case reports · 2026Article
- Pathological complete remission of pulmonary epithelioid hemangioendothelioma: a case report and literature review.Journal of cardiothoracic surgery · 2026Review
- YAP1::TFE3 mediates endothelial-to-mesenchymal plasticity in epithelioid hemangioendothelioma.Molecular oncology · 2026Article
- A 76-year-old man with hemoptysis and a groin nodule: A case report.SAGE open medical case reports · 2026Article
- Pulsed ultrasound-stimulated microbubbles alter the tumor blood supply to enhance the efficacy of high-intensity focused ultrasound ablation of vascular tumors.Frontiers in oncology · 2026Article
- Radiation Therapy for Maxillary Sinus Epithelioid Hemangioendothelioma: A Case Report and Literature Review.Cureus · 2025Article
- Vascular penetration sign: dual-phase enhanced CT manifestations of atypical liver abscess caused by Klebsiella pneumoniae.European radiology · 2025Article
- The efficacy and safety of gemcitabine and docetaxel in pseudomyogenic hemangioendothelioma: a multi-center experience.BMC cancer · 2025Article
- Gene Fusions as Potential Therapeutic Targets in Soft Tissue Sarcomas.Biomolecules · 2025Review
- The use of pegylated liposomal doxorubicin in metastatic soft tissue sarcoma.Acta oncologica (Stockholm, Sweden) · 2025Article
- Epithelioid hemangioendothelioma of the anterior mediastinum.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Total talectomy and reconstruction using unrestricted 3D printed prosthesis for pediatric talus hemangioendothelioma.Bone reports · 2025Article
- Article
- Nab-Paclitaxel Based Chemotherapy in the Treatment of Advanced Epithelioid Hemangioendothelioma: A Single-Institution Experience.Cancer management and research · 2025Article
- Auricular epithelioid hemangioendothelioma: Two cases first diagnosed as auricular pseudocyst.Oncology letters · 2025Article
- Epithelioid hemangioendothelioma prognosis and outcome: report of two challenging cases.Journal of cardiothoracic surgery · 2024Article
- Subcapital Femoral Neck Fracture in a Professionally Active Patient Undergoing Palliative Treatment for Endothelial Cell-Derived Epithelioid Haemangioendothelioma (EHE).Reports (MDPI) · 2024Article
- Malignant epithelioid hemangioendothelioma of the sternum: A case report and literature review.JTCVS techniques · 2024Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
opinion statementEpithelioid hemangioendothelioma (EHE) is an extremely rare sarcoma, as such it can pose a clinical dilemma based solely on its rarity. Also, the spectrum of disease varies greatly between an indolent disease and aggressive disease with widespread metastases. In our clinical practice, the primary focus has been to get a handle on the aggressive nature of the disease, which will then dictate how urgently one needs to treat the patient. Pathological review with immunohistochemistry and molecular characterization is paramount. Our treatment strategy is watch-and-wait versus active therapy on clinical trial or based on results of prior clinical trials. There is evidence to support the use of chemotherapeutics and targeted therapies specifically focusing on anti-angiogenesis. The current landscape of oncology with the emergence and excitement of immunotherapy could also translate in a role for immunotherapy in this disease. While rare, there is certainly no reason that research and trials for patients with EHE should not remain on utmost importance for those of us who specialize in the treatment of sarcomas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.