Evidence map›Paper›PMID 29546436›Full record

ArticleEuropean biophysics journal : EBJ2018

Effects of pH and aggregation in the human prion conversion into scrapie form: a study using molecular dynamics with excited normal modes.

Angelica Nakagawa Lima, Ronaldo Junio de Oliveira, Antônio Sérgio Kimus Braz, Maurício Garcia de Souza Costa, David Perahia, Luis Paulo Barbour Scott

Abstract read
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In one paragraph

Article in European biophysics journal : EBJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Angelica Nakagawa LimaLaboratório de Biologia Computacional e Bioinformática, Universidade Federal do ABC, Santo André, SP, Brazil.
Ronaldo Junio de OliveiraLaboratório de Biofísica Teórica, Departamento de Física, Instituto de Ciências Exatas, Naturais e Educação, Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
Antônio Sérgio Kimus BrazLaboratório de Biologia Computacional e Bioinformática, Universidade Federal do ABC, Santo André, SP, Brazil.
Maurício Garcia de Souza CostaFundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
David PerahiaLaboratorie de Biologie et Pharmacologie Appliquée, Ecole Normale Supérieure Paris-Saclay, Cachan, France.
Luis Paulo Barbour ScottLaboratório de Biologia Computacional e Bioinformática, Universidade Federal do ABC, Santo André, SP, Brazil. luis.scott@ufabc.edu.br.
Universidade Federal do ABC · BRÉcole Normale Supérieure Paris-Saclay · FRFundação Oswaldo Cruz · BRUniversidade Federal do Triângulo Mineiro · BR

Funding

Fapesp 2013/23669-3
6 · The paper itself

Abstract

There are two different prion conformations: (1) the cellular natural (PrP

Indexed as

Molecular Dynamics SimulationProtein AggregatesHumansHydrogen-Ion ConcentrationProtein Conformation, beta-StrandProtein FoldingPrPC ProteinsPrPSc ProteinsProtein AggregatesPrPC ProteinsPrPSc ProteinsCellular prion PrPCExcited normal modesMolecular dynamicsScrapie prion PrPScStructural transition

Identifiers

PMID29546436
OpenAlexW2791692278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.