ArticleAge and ageing2018
Longitudinal changes in physical function and physical activity in older adults.
Article in Age and ageing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Impact of physical activity and exercise training on health-related quality of life in older adults: an umbrella review.GeroScience · 2025Pooled it
- Association Between Physical Activity Levels and Life Functioning in Korean Older Adults: A Cross-Sectional Analysis of the 2024 Korea National Health and Nutrition Examination Survey.Healthcare (Basel, Switzerland) · 2026Article
- Effects of the Otago Exercise Program on Physical Function Performance Related to Falls in the Elderly: A Meta-Analysis of Randomized Controlled Trials.Healthcare (Basel, Switzerland) · 2026Review
- Article
- Joint effect of physical capacity and physical activity predicts depression progression in middle-aged and older Chinese adults.Journal of global health · 2026Observational
- Alcohol, aging, and the gut microbiome: Intersections of immunity, barrier dysfunction, and disease.Alcohol (Fayetteville, N.Y.) · 2025Review
- Reciprocal Associations Between Relative or Absolute Physical Activity, Walking Performance, and Autonomy in Outdoor Mobility Among Older Adults: A 4-Year Follow-Up.Journal of aging and health · 2025Article
- The association between sensor-based assessments of daily physical activity patterns and physical fitness in older adults: a systematic review and meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025Review
- Community Specialist Teams for Older Persons (CST-OP) at risk of, or living with frailty in Ireland: a prospective cohort study of a new model of integrated care for community dwelling older adults.BMC primary care · 2025Observational
- Reciprocal Associations Between Trajectories of Physical Activity and Physical Function Among Older Women: Findings From the Australian Longitudinal Study on Women's Health.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Association between pet ownership and physical function at discharge in hospitalized older adults: A retrospective observational study.PloS one · 2025Observational
- Toward a Medication Information Literacy Indicator System for Older Adults: A Delphi Study.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- Building Medication Profiles in the Elderly: a Qualitative Study Based on Medication Information Literacy in a Long-Term Care Facility.Clinical interventions in aging · 2024Article
- Prospective association of occupational and leisure-time physical activity with orthostatic blood pressure changes in older adults.Scientific reports · 2023Article
- Age and Sex Differences in Physical Activity of Portuguese Adults and Older Adults.Healthcare (Basel, Switzerland) · 2023Article
- Convergent validity and inter-rater reliability of a lower-limb multimodal physical function assessment in community-dwelling older adults.Frontiers in aging · 2023Article
- Pet Ownership and Maintenance of Physical Function in Older Adults-Evidence From the Baltimore Longitudinal Study of Aging (BLSA).Innovation in aging · 2023Article
- Changes in Objectively Measured Physical Activity Are Associated With Perceived Physical and Mental Fatigability in Older Men.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Bidirectional associations of accelerometer-assessed physical activity and sedentary time with physical function among older English adults: the EPIC-Norfolk cohort study.European journal of ageing · 2022Article
- Cardiometabolic risk factors and cardiovascular disease predictions in older African and European Americans.Preventive medicine reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundphysical function (PF) and physical activity (PA) both decline as adults age and have been linked to negative outcomes, including dementia, depression and cardiovascular diseases. Although declines in each are associated with numerous negative outcomes, the longitudinal relationship between these two measures is unclear.
objectiveto examine the dynamic, bidirectional associations between declines in PF and PA.
designprospective cohort.
settingthe Monongahela-Youghiogheny Healthy Aging Team (MYHAT) study. SUBJECTS: about 1,404 men and women, 76.96 ± 7.2 years, 62.4% female and 95.2% white.
methodsover nine annual assessment cycles, PF was evaluated via the timed Up-and-Go task and PA via a self-reported questionnaire. Piecewise latent growth models examined bidirectional associations between PA and PF to determine whether the initial values (intercept) or early slope (cycles 1-5) (in either PF or PA) predicted later slope (cycles 5-9) (in either PF or PA).
resultsinitial PF significantly predicted early (standardised β= -0.10, P < 0.001) and later (standardised β= -0.09, P = 0.01) PA slopes. Initial PA significantly predicted later (standardised β = -0.09, P = 0.04) but not early PF slope. Associations were independent of baseline memory test scores, baseline cognitive status, later cognitive status and age. Early physical function slope neither predicts later PA slope nor did early PA slope predict later PF slope (both P values >0.10).
conclusionsthe relationship between PF and PA is bidirectional, with PF more consistently predicting declines of PA, both in the short- and long-term. Intervening on PF impairments may improve PA engagement, which could in turn promote PF and translate to beneficial effects on cognitive function, cardiovascular health and mood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.