ArticleAge and ageing2018
Evaluating frailty scores to predict mortality in older adults using data from population based electronic health records: case control study.
Article in Age and ageing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06965972 (Prospective Cohort for the Study of Phenotypic Clusters, Progression Paths and Outcomes of Frailty and Dependence), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Cohort for the Study of Phenotypic Clusters, Progression Paths and Outcomes of Frailty and Dependence: The Spanish CohorFES
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Identifying older adults with frailty approaching end-of-life: A systematic review.Palliative medicine · 2021Pooled it
- Identification of patients with potential palliative care needs: A systematic review of screening tools in primary care.Palliative medicine · 2020Pooled it
- Article
- Differences in survival and healthcare utilization amongst nursing home residents with advanced dementia and frailty compared to other end-of-life conditions: a retrospective cohort study.BMC palliative care · 2025Article
- Gabapentinoids and Risk of Hip Fracture.JAMA network open · 2024Article
- Frailty Indicator over the Adult Life Cycle as a Predictor of Healthcare Expenditure and Mortality in the Short to Midterm.Healthcare (Basel, Switzerland) · 2024Article
- The electronic frailty index and outcomes in patients with myocardial infarction.Age and ageing · 2024Article
- Deep learning-based prediction of one-year mortality in Finland is an accurate but unfair aging marker.Nature aging · 2024Article
- Identifying Frailty in Administrative Databases: A Narrative Review.The Journal of frailty & aging · 2024Review
- Association between subjective social status and physical frailty in older adults in India: perceived discrimination and III-treatment as mediators and moderators.Aging clinical and experimental research · 2023Article
- Perspectives of healthcare professionals and older patients on shared decision-making for treatment escalation planning in the acute hospital setting: a systematic review and qualitative thematic synthesis.EClinicalMedicine · 2023Article
- Change in a Claims-Based Frailty Index, Mortality, and Health Care Costs in Medicare Beneficiaries.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Prevalence and associated factors of frailty among community dweller older adults living in Gondar town, northwest, Ethiopia: a community based cross-sectional study.BMC public health · 2023Article
- Lipidomic signatures from physically frail and robust older adults at hospital admission.GeroScience · 2022Article
- A Novel Digital Nutrition Diary for Geriatric Patients at High Risk of Frailty Syndrome.Nutrients · 2022Article
- Prevalence of Frailty in the Middle East: Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2022Review
- Frailty Changes Predict Mortality in 4 Longitudinal Studies of Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- Article
- Changes in a Frailty Index and Association with Mortality.Journal of the American Geriatrics Society · 2021Article
- The Electronic Frailty Index is Associated with Increased Infection and All-Cause Mortality Among Older Patients with Primary Lung Cancer: A Cohort Study.Clinical interventions in aging · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundrecognising that a patient is nearing the end of life is essential, to enable professional carers to discuss prognosis and preferences for end of life care.
objectiveinvestigate whether an electronic frailty index (eFI) generated from routinely collected data, can be used to predict mortality at an individual level.
designhistorical prospective case control study.
settingUK primary care electronic health records. SUBJECTS: 13,149 individuals age 75 and over who died between 01/01/2015 and 01/01/2016, 1:1 matched by age and sex to individuals with no record of death in the same time period.
methodstwo subsamples were randomly selected to enable development and validation of the association between eFI 3 months prior to death and mortality. Receiver operator characteristic (ROC) analyses were used to examine diagnostic accuracy of eFI at 3 months prior to death.
resultsan eFI > 0.19 predicted mortality in the development sample at 75% sensitivity and 69% area under received operating curve (AUC). In the validation dataset this cut point gave 76% sensitivity, 53% specificity.
conclusionsthe eFI measured at a single time point has low predictive value for individual risk of death, even 3 months prior to death. Although the eFI is a strong predictor or mortality at a population level, its use for individuals is far less clear.
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