Evidence map›Paper›PMID 29546248›Full record

ArticlemSystems

Development of the Human Mycobiome over the First Month of Life and across Body Sites.

Tonya L Ward, Maria Gloria Dominguez-Bello, Tim Heisel, Gabriel Al-Ghalith, Dan Knights, Cheryl A Gale

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 110 papers.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04054635 nacompletednot on this map

A Randomized Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children

TypeinterventionalSponsorUniversity of ManitobaRan2019 to 2023Enrolled84ConditionsEarly Childhood CariesArmsSilver diamine fluoride
NCT05427760 nacompletednot on this map

Effect of Using Oxygen on the Diaper Dermatitis in Infants

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2022 to 2023Enrolled103ConditionsDiaper Rash, Diaper DermatitisArmsOxygen
3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 190 citations in OpenAlex.

  1. Fungi form interkingdom microbial communities in the primordial human gut that develop with gestational age.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Trial
  2. Review
  3. The gut-lung axis in early life: microbiome-associated mechanisms and clinical relevance.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. [Comparative analysis of microbial communities in different oral ecological niches of preschool children].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Article
  8. Fungal Reactive Oxygen Species Secreted byJournal of fungi (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tonya L WardBioTechnology Institute, University of Minnesota, St. Paul, Minnesota, USA.
Maria Gloria Dominguez-BelloDepartments of Biochemistry and Microbiology and Anthropology, Rutgers University, New Brunswick, New Jersey, USA.
Tim HeiselDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Gabriel Al-GhalithBioinformatics and Computational Biology, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0002-6953-6319
Dan KnightsBioTechnology Institute, University of Minnesota, St. Paul, Minnesota, USA.
Cheryl A GaleDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0002-0185-8645
University of Minnesota · USRutgers, The State University of New Jersey · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Disappearing gastrointestinal microbiota in epidemic obesity.R01DK090989 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BLASER, MARTIN J · 2010 to 2015
$7.4M
Early life antibiotics, gut microbiome development, and risk of childhood obesityR01AI121383 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI GERBER, JEFFREY STEPHEN, KNIGHTS, DAN · 2016 to 2020
$3.7M
NCATS NIH HHS UL1 TR000114NIAID NIH HHS R01 AI121383NIDDK NIH HHS R01 DK090989
6 · The paper itself

Abstract

With the advent of next-generation sequencing and microbial community characterization, we are beginning to understand the key factors that shape early-life microbial colonization and associated health outcomes. Studies characterizing infant microbial colonization have focused mostly on bacteria in the microbiome and have largely neglected fungi (the mycobiome), despite their relevance to mucosal infections in healthy infants. In this pilot study, we characterized the skin, oral, and anal mycobiomes of infants over the first month of life (

Indexed as

fungiinfantITS2microbiomemycobiome

Identifiers

PMID29546248
PMCPMC5840654
OpenAlexW2791585845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.