Evidence map›Paper›PMID 29546247›Full record

ArticleInternational journal of cancer and clinical research2017

Physiological Effort in Submaximal Fitness Tests Predicts Weight Loss in Overweight and Obese Men with Prostate Cancer in a Weight Loss Trial.

Andrew D Frugé, John A Dasher, David Bryan, Soroush Rais-Bahrami, Wendy Demark-Wahnefried, Gary R Hunter

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cancer and clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01886677 (Exploring the Impact of Negative Energy Balance in Men With Prostate Cancer), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01886677 nacompletednot on this map

Exploring the Impact of Negative Energy Balance in Men With Prostate Cancer

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2012 to 2015Enrolled40ConditionsProstate CancerArmsImmediate diet and exercise intervention, Delayed diet and exercise intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrew D FrugéDepartment of Nutrition Sciences, University of Alabama at Birmingham (UAB), USA.
John A DasherUAB School of Medicine, Birmingham, Alabama, USA.
David BryanDepartment of Nutrition Sciences, University of Alabama at Birmingham (UAB), USA.
Soroush Rais-BahramiDepartment of Urology, UAB School of Medicine, Birmingham, Alabama, USA.
Wendy Demark-WahnefriedDepartment of Nutrition Sciences, University of Alabama at Birmingham (UAB), USA.
Gary R HunterDepartment of Human Studies, UAB, Birmingham, Alabama, USA.
University of Alabama at Birmingham · USUniversity of Alabama · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
Cancer Prevention & Control Training ProgramR25CA047888 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DEMARK-WAHNEFRIED, WENDY, MENESES, KAREN M · 1988 to 2016
$11.2M
Exploring the Impact of Negative Energy Balance in Men with Prostate CancerR21CA161263 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DEMARK-WAHNEFRIED, WENDY · 2012 to 2013
$341k
NCI NIH HHS P30 CA013148NCI NIH HHS R21 CA161263NCI NIH HHS R25 CA047888NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

backgroundObesity and weight gain after the diagnosis of prostate cancer are associated with an increased risk of prostate cancer recurrence and mortality; individualized plans to help prostate cancer survivors maintain or lose weight may be beneficial for recurrence risk reduction. Herein, we explore whether gains in cardiovascular fitness predict successful weight loss in men participating in a weight loss trial (NCT01886677).

methodsForty men were randomized to receive twice-weekly in-person and telephone-based guidance on calorie-restricted diets and aerobic exercise to promote ~0.91 kg/week weight loss, or wait-list control. Thirty-two men completed submaximal VO

resultsMen lost 3.4 kg in 50 ± 23 days on the study. Multivariate linear regression indicated weight change was associated with change in PE at stage 2TT (Partial R = 0.635, p < 0.001), days on study (Partial R = -0.589, p = 0.002) and change in caloric intake (Partial R = 0.457, p = 0.019).

conclusionsUntrained men experiencing elevated heart rates during stage 2TT at baseline were able to achieve greater weight loss over the study period; this association was strengthened by a decrease in PE at the same level from baseline to follow-up concomitant with reduced caloric intake. Therefore, for these middle-aged and older men with lower aerobic fitness, exercise appears to be a key factor in achieving higher degrees of weight loss.

Indexed as

Aerobic fitnessExerciseObesityProstatic neoplasmsWeight loss

Identifiers

PMID29546247
PMCPMC5846475
OpenAlexW2766604697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.