Evidence map›Paper›PMID 29545874›Full record

ArticleExperimental and therapeutic medicine2018

GDF11/BMP11 as a novel tumor marker for liver cancer.

Yong-Hui Zhang, Lian-Hong Pan, Yi Pang, Jin-Xin Yang, Meng-Jia Lv, Feng Liu, Xue-Feng Qu, Xin-Xin Chen, Hua-Jun Gong, Dan Liu and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. PCBP2 facilitates miR-93-5p-mediated repression ofMolecular therapy. Nucleic acids · 2026
    Article
  2. Review
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  4. GDF11: An emerging therapeutic target for liver diseases and fibrosis.Journal of cellular and molecular medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yong-Hui ZhangDepartment of Basic Medical Science, Chongqing Three Gorges Medical College, Chongqing 404120, P.R. China.
Lian-Hong PanChongqing Engineering Research Center of Antitumor Natural Drugs, Chongqing 404120, P.R. China.
Yi PangChongqing Engineering Research Center of Antitumor Natural Drugs, Chongqing 404120, P.R. China.
Jin-Xin YangChongqing Engineering Research Center of Antitumor Natural Drugs, Chongqing 404120, P.R. China.
Meng-Jia LvChongqing Engineering Research Center of Antitumor Natural Drugs, Chongqing 404120, P.R. China.
Feng LiuChongqing Engineering Research Center of Antitumor Natural Drugs, Chongqing 404120, P.R. China.
Xue-Feng QuDepartment of Nutrition and Food Hygiene, Zhejiang Academy of Medical Sciences, Hangzhou, Zhejiang 310013, P.R. China.
Xin-Xin ChenChongqing Engineering Research Center of Antitumor Natural Drugs, Chongqing 404120, P.R. China.
Hua-Jun GongChongqing Engineering Research Center of Antitumor Natural Drugs, Chongqing 404120, P.R. China.
Dan LiuDepartment of Basic Medical Science, Chongqing Three Gorges Medical College, Chongqing 404120, P.R. China.
Yong WeiKey Laboratory of Intelligent Information Processing and Control, College of Electronic and Information Engineering, Chongqing Three Gorges University, Chongqing 404110, P.R. China.
Chongqing Three Gorges University · CNZhejiang Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth differentiation factor 11 (GDF11), also known as bone morphogenetic protein 11, a member of the transforming growth factor-β superfamily, has been reported to be involved in colorectal cancer. However, the roles of GDF11 in Chinese patients with liver cancer and the underlying mechanisms have remained elusive. The present study assessed the expression of GDF11 in 10 paired samples of cancerous and normal tissues from Chinese liver cancer patients. The results indicated that the expression of GDF11 was significantly lower in cancerous tissues than in normal tissues.

Indexed as

bone morphogenetic protein 11growth differentiation factor 11liver cancerSmad2/3tumor marker

Identifiers

PMID29545874
PMCPMC5841059
OpenAlexW2791970991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.