Evidence map›Paper›PMID 29545839›Full record

ArticleExperimental and therapeutic medicine2018

Finite element analysis of compression fractures at the thoracolumbar junction using models constructed from medical images.

Daisuke Nakashima, Tsukasa Kanchiku, Norihiro Nishida, Saki Ito, Junji Ohgi, Hidenori Suzuki, Yasuaki Imajo, Masahiro Funaba, Xian Chen, Toshihiko Taguchi

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Prevalence of vertebral fractures at death.Journal of bone and mineral metabolism · 2025
    Article
  2. Article
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  4. Article
  5. Romosozumab Enhances Vertebral Bone Structure in Women With Low Bone Density.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Letter to the Editor concerning "Osteoporotic thoracolumbar compression fractures: long-term retrospective comparison between vertebroplasty and conservative treatment" by K. Martikos et al. [Eur Spine J (2018) doi: 10.1007/s00586-018-5605-1].European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daisuke NakashimaDepartment of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.
Tsukasa KanchikuDepartment of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.
Norihiro NishidaDepartment of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.
Saki ItoDepartment of Mechanical Engineering, Yamaguchi University, Ube, Yamaguchi 755-8611, Japan.
Junji OhgiDepartment of Mechanical Engineering, Yamaguchi University, Ube, Yamaguchi 755-8611, Japan.
Hidenori SuzukiDepartment of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.
Yasuaki ImajoDepartment of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.
Masahiro FunabaDepartment of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.
Xian ChenDepartment of Mechanical Engineering, Yamaguchi University, Ube, Yamaguchi 755-8611, Japan.
Toshihiko TaguchiDepartment of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vertebral fractures commonly occur at the thoracolumbar junction. These fractures can be treated with mild residual deformity in many cases, but are reportedly associated with increased risk of secondary vertebral fractures. In the present study, a three-dimensional (3D) whole spine model was constructed using the finite element method to explore the mechanism of development of compression fractures. The 3D model of the whole spine, from the cervical spine to the pelvis, was constructed from computed tomography (CT) images of an adult male. Using a normal spine model and spine models with compression fractures at the T11, T12 or L1 vertebrae, the distribution of strain was analyzed in the vertebrae after load application. The normal spine model demonstrated greater strain around the thoracolumbar junction and the middle thoracic spine, while the compression fracture models indicated focused strain at the fracture site and adjacent vertebrae. Increased load time resulted in the extension of the strain region up to the middle thoracic spine. The present findings, that secondary vertebral fractures commonly occur around the fracture site, and may also affect the thoracic vertebrae, are consistent with previous clinical and experimental results. These results suggest that follow-up examinations of compression fractures at the thoracolumbar junction should include the thoracic spine and adjacent vertebrae. The current data also demonstrate that models created from CT images can be used for various analyses.

Indexed as

computed tomographyfinite element methodsecondary vertebral fracturespinal compression fracturethoracolumbar junction

Identifiers

PMID29545839
PMCPMC5841061

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.