Evidence map›Paper›PMID 29545592›Full record

Trial reportBone marrow transplantation2018

Efficacy and safety of keratinocyte growth factor (palifermin) for prevention of oral mucositis in TBI-based allogeneic hematopoietic stem cell transplantation.

Volker Schmidt, Dietger Niederwieser, Thomas Schenk, Gerhard Behre, Anne Klink, Christian Pfrepper, Axel Hinke, Dietrich W Beelen, Christian Junghanss, Lutz Uharek and 4 more

Abstract readLetterMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Bone marrow transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Radiomitigators: Breakthroughs in Post-Radiation Recovery.Antioxidants (Basel, Switzerland) · 2026
    Review
  3. Oral mucositis management in hematopoietic cell transplantation in Australia and New Zealand (CAN EAT Survey).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Volker SchmidtDepartment of Haematology and Medical Oncology, Clinic of Internal Medicine II, University Hospital Jena, Jena, Germany.
Dietger NiederwieserDepartment of Haematology, Oncology and Hemostaseology, University Clinical Center, University of Leipzig, Leipzig, Germany.
Thomas SchenkDepartment of Haematology and Medical Oncology, Clinic of Internal Medicine II, University Hospital Jena, Jena, Germany.
Gerhard BehreDepartment of Haematology, Oncology and Hemostaseology, University Clinical Center, University of Leipzig, Leipzig, Germany.
Anne KlinkDepartment of Haematology and Medical Oncology, Clinic of Internal Medicine II, University Hospital Jena, Jena, Germany.
Christian PfrepperDepartment of Haematology, Oncology and Hemostaseology, University Clinical Center, University of Leipzig, Leipzig, Germany.
Axel HinkeWiSP Wissenschaftlicher Service Pharma GmbH, Langenfeld, Germany.
Dietrich W BeelenDepartment of Bone Marrow Transplantation, West German Cancer Center, Faculty of Medicine, University Duisburg-Essen, Essen, Germany.
Christian JunghanssDepartment of Haematology, Oncology, Palliative Care, University of Rostock, Rostock, Germany.
Lutz UharekDepartment of Hematology, Oncology and Tumorimmunology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany.
William H KrügerInternal Medicine C (Hematology and Oncology, Palliative Care, Transplant Centre), University Hospital Greifswald, Ernst-Moritz-Arndt-University, Greifswald, Germany.
Andreas HochhausDepartment of Haematology and Medical Oncology, Clinic of Internal Medicine II, University Hospital Jena, Jena, Germany.
Herbert G SayerDepartment of Haematology and Medical Oncology, Clinic of Internal Medicine II, University Hospital Jena, Jena, Germany. Herbert.Sayer@helios-gesundheit.de.
East German Study Group for Hematology and Oncology (OSHO)
Jena University Hospital · DEUniversity of Rostock · DECharité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultFemaleFibroblast Growth Factor 7Hematopoietic Stem Cell TransplantationHumansMaleMiddle AgedStomatitisTransplantation, HomologousTreatment OutcomeWhole-Body IrradiationYoung AdultFGF7 protein, humanFibroblast Growth Factor 7

Identifiers

PMID29545592
OpenAlexW2789446825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.