Evidence map›Paper›PMID 29545390›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)2018

Elongator complex is required for long-term olfactory memory formation in

Dinghui Yu, Ying Tan, Molee Chakraborty, Seth Tomchik, Ronald L Davis

Open access · diamondAbstract read
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Elongator Subunit 3 (Elp3) Is Required for Zebrafish Trunk Development.International journal of molecular sciences · 2020
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Dinghui YuDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.
Ying TanDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
Molee ChakrabortyDepartment of Neuroscience, Scripps Research Institute Florida, Jupiter, Florida 33458, USA.
Seth TomchikDepartment of Neuroscience, Scripps Research Institute Florida, Jupiter, Florida 33458, USA.
Ronald L DavisDepartment of Neuroscience, Scripps Research Institute Florida, Jupiter, Florida 33458, USA.
Max Planck Florida Institute for Neuroscience · USBaylor College of Medicine · USScripps Research Institute · USTexas Children's Hospital · US

Funding

Biology of memoryR35NS097224 · NINDS · UNIVERSITY OF FLORIDA · PI DAVIS, RONALD L · 2017 to 2024
$9.1M
Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8M
Olfactory memory trace formation in DrosophilaR01NS052351 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI DAVIS, RONALD L · 2006 to 2016
$4.2M
Molecular Biology of Drosophila Learning and MemoryR37NS019904 · NINDS · SCRIPPS FLORIDA · PI DAVIS, RONALD L · 2013 to 2016
$1.9M
NICHD NIH HHS U54 HD083092NINDS NIH HHS R01 NS052351NINDS NIH HHS R35 NS097224NINDS NIH HHS R37 NS019904
6 · The paper itself

Abstract

The evolutionarily conserved Elongator Complex associates with RNA polymerase II for transcriptional elongation. Elp3 is the catalytic subunit, contains histone acetyltransferase activity, and is associated with neurodegeneration in humans. Elp1 is a scaffolding subunit and when mutated causes familial dysautonomia. Here, we show that

Indexed as

SmellAnimalsAnimals, Genetically ModifiedConditioning, ClassicalDrosophila melanogasterDrosophila ProteinsGene Knockdown TechniquesHistone AcetyltransferasesMemory, Long-TermNerve Tissue ProteinsNeuronsOlfactory PathwaysDrosophila ProteinsELP3 protein, DrosophilaHistone AcetyltransferasesNerve Tissue Proteins

Identifiers

PMID29545390
PMCPMC5855525
OpenAlexW2789606898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.