Evidence map›Paper›PMID 29545272›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Coordination to lanthanide ions distorts binding site conformation in calmodulin.

Sean C Edington, Andrea Gonzalez, Thomas R Middendorf, D Brent Halling, Richard W Aldrich, Carlos R Baiz

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 130 citations in OpenAlex.

  1. Pooled it
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  17. Bioelectricity and molecular signaling.Biophysical journal · 2024
    Article
  18. Article
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  20. Ultrafast Spectroscopy Reveals Slow Water Dynamics in Biocondensates.Journal of the American Chemical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sean C EdingtonDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712-1224.ORCID 0000-0002-5894-8801
Andrea GonzalezDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712-1224.
Thomas R MiddendorfDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712-0805.
D Brent HallingDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712-0805.
Richard W AldrichDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712-0805 raldrich@mail.utexas.edu.ORCID 0000-0001-7254-5876
Carlos R BaizDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712-1224.
The University of Texas at Austin · US

Funding

Mechanisms of Calcium-Calmodulin Mediated Ion Channel GatingR01NS077821 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI ALDRICH, RICHARD · 2011 to 2021
$4.7M
NINDS NIH HHS R01 NS077821
6 · The paper itself

Abstract

The Ca

Indexed as

Protein ConformationBinding SitesCalciumCalmodulinHumansLanthanoid Series ElementsModels, MolecularProtein BindingProtein DomainsCalciumCALM1 protein, humanCalmodulinLanthanoid Series Elements2D IRcalmodulinEF handFTIRlanthanide

Identifiers

PMID29545272
PMCPMC5889669
OpenAlexW2794150445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.