ArticleJournal of the American Heart Association2018
Associations Between Ambient Particle Radioactivity and Blood Pressure: The NAS (Normative Aging Study).
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Does protracted radon exposure play a role in the development of dementia?Environmental research · 2022Pooled it
- Exposure to Air Pollution and Particle Radioactivity With the Risk of Ventricular Arrhythmias.Circulation · 2020Trial
- Temporal trends of particle gross β-activity and PMAir quality, atmosphere, & health · 2023Article
- Radon sampling methodologies: A case for accurate, accessible measurements using household instruments.Journal of the Air & Waste Management Association (1995) · 2023Article
- Synergistic Effects of Particle Radioactivity (Gross β Activity) and Particulate Matter ≤2.5 μm Aerodynamic Diameter on Cardiovascular Disease Mortality.Journal of the American Heart Association · 2022Article
- Geomagnetic disturbances reduce heart rate variability in the Normative Aging Study.The Science of the total environment · 2022Article
- Assessing Exposure to Unconventional Oil and Gas Development: Strengths, Challenges, and Implications for Epidemiologic Research.Current environmental health reports · 2022Review
- Associations between solar and geomagnetic activity and peripheral white blood cells in the Normative Aging Study.Environmental research · 2022Article
- The role of solar and geomagnetic activity in endothelial activation and inflammation in the NAS cohort.PloS one · 2022Article
- Solar Activity Is Associated With Diastolic and Systolic Blood Pressure in Elderly Adults.Journal of the American Heart Association · 2021Article
- Short-term exposure to PMJournal of hazardous materials · 2021Article
- Sources of indoor PMEnvironmental research · 2021Article
- Unconventional oil and gas development and ambient particle radioactivity.Nature communications · 2020Article
- Ambient particle radioactivity and gestational diabetes: A cohort study of more than 1 million pregnant women in Massachusetts, USA.The Science of the total environment · 2020Article
- The Role of Ambient Particle Radioactivity in Inflammation and Endothelial Function in an Elderly Cohort.Epidemiology (Cambridge, Mass.) · 2020Article
- Association between ambient beta particle radioactivity and lower hemoglobin concentrations in a cohort of elderly men.Environment international · 2020Article
- Article
- Short-term exposures to particulate matter gamma radiation activities and biomarkers of systemic inflammation and endothelial activation in COPD patients.Environmental research · 2020Article
- Short-term ambient particle radioactivity level and renal function in older men: Insight from the Normative Aging Study.Environment international · 2019Article
- Associations between ambient particle radioactivity and lung function.Environment international · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThe cardiovascular effects of low-level environmental radiation exposures are poorly understood. Although particulate matter (PM) has been linked to cardiovascular morbidity and mortality, and elevated blood pressure (BP), the properties promoting its toxicity remain uncertain. Addressing a knowledge gap, we evaluated whether BP increased with higher exposures to radioactive components of ambient PM, herein referred to as particle radioactivity (PR). METHODS AND
resultsWe performed a repeated-measures analysis of 852 men to examine associations between PR exposure and BP using mixed-effects regression models. As a surrogate for PR, we used gross β activity, measured by the US Environmental Protection Agency's radiation monitoring network. Higher PR exposure was associated with increases in both diastolic BP and systolic BP, for exposures from 1 to 28 days. An interquartile range increase in 28-day PR exposure was associated with a 2.95-mm Hg increase in diastolic BP (95% confidence interval, 2.25-3.66;
conclusionsThis is the first study to demonstrate the potential adverse effects of PR on both systolic and diastolic BPs. These were independent and similar in magnitude to those of PM ≤2.5 µm, black carbon, and particle number. Understanding the effects of particle-bound radionuclide exposures on BP may have important implications for environmental and public health policy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.