Evidence map›Paper›PMID 29545256›Full record

ArticleBlood advances2018

Epidemiology, clinical features, and outcome of HTLV-1-related ATLL in an area of prevalence in the United States.

Luis Malpica, Agustin Pimentel, Isildinha M Reis, Eduardo Gotuzzo, Lazaros Lekakis, Krishna Komanduri, Thomas Harrington, Glen N Barber, Juan C Ramos

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

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  9. Epidemiology and Clinical Outcomes of HTLV-1: A Comprehensive Narrative Review of Endemic and Nonendemic Regions.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Luis MalpicaInternal Medicine Program, Jackson Memorial Hospital.ORCID 0000-0002-7082-1846
Agustin PimentelDivision of Oncology, Department of Medicine, and.
Isildinha M ReisDivision of Biostatistics, Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL.
Eduardo GotuzzoAlexander von Humboldt Institute of Tropical Medicine and Infectious Diseases, Department of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru; and.
Lazaros LekakisDivision of Hematology, Department of Medicine.
Krishna KomanduriDivision of Hematology, Department of Medicine.
Thomas HarringtonDivision of Hematology, Department of Medicine.
Glen N BarberSylvester Comprehensive Cancer Center, and.
Juan C RamosDivision of Hematology, Department of Medicine.
Sylvester Comprehensive Cancer Center · USUniversity of Miami · USJackson Memorial Hospital · USUniversidad Peruana Cayetano Heredia · PE

Funding

Epigenetic Targeting of Afro-Caribbean Variant of HTLV-1 Related Adult T-cell Leukemia-lymphomaR01CA223232 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RAMOS, JUAN CARLOS · 2018 to 2022
$1.7M
NCI NIH HHS R01 CA223232
6 · The paper itself

Abstract

Adult T-cell leukemia/lymphoma (ATLL) is a fatal disease caused by human T-cell leukemia virus type 1 (HTLV-1). We retrospectively analyzed 195 patients with ATLL (lymphomatous n = 96, acute n = 80, unfavorable chronic n = 7, chronic n = 5, smoldering n = 3, and unclassified n = 4) diagnosed between 1987 and 2016 (median age 52 years, 77% Afro-Caribbean). Hypercalcemia was associated with acute ATLL (65%, vs 23% lymphomatous) (

Indexed as

Human T-lymphotropic virus 1AdultAgedBiomarkersCombined Modality TherapyComorbidityFemaleHTLV-I InfectionsHumansKaplan-Meier EstimateLeukemia-Lymphoma, Adult T-CellMaleMiddle AgedNeoplasm StagingPrevalenceRetrospective StudiesBiomarkers

Identifiers

PMID29545256
PMCPMC5873228
OpenAlexW2789917776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.