Evidence map›Paper›PMID 29545248›Full record

SynthesisAJNR. American journal of neuroradiology2018

Endovascular Treatment of Very Large and Giant Intracranial Aneurysms: Comparison between Reconstructive and Deconstructive Techniques-A Meta-Analysis.

F Cagnazzo, D Mantilla, A Rouchaud, W Brinjikji, P-H Lefevre, C Dargazanli, G Gascou, C Riquelme, P Perrini, D di Carlo and 2 more

Registry-linked trialOpen access · hybridAbstract readComparative StudyMeta-Analysis
In one paragraph

Synthesis in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06541275 (Assessment of the Dynamic Reduction in Volume and Prolonged Shrinkage of Giant and Symptomatic Cerebral Aneurysms Following Combined Endovascular Interventions), which is not on this map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06541275 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Assessment of the Dynamic Reduction in Volume and Prolonged Shrinkage of Giant and Symptomatic Cerebral Aneurysms Following Combined Endovascular Interventions

TypeobservationalSponsorNational Centre for Neurosurgery, Republic of KazakhstanRan2024 to 2026Enrolled102ConditionsBrain AneurysmArmsbrain MRI and CT
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  5. The "pipe-anchor" technique: A method for intra-aneurysmal loop reduction using a partially unsheathed pipeline stent.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

F CagnazzoFrom the Neuroradiology Department (F.C., D.M., P.-H.L., C.D., G.G., C.R., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France f.cagnazzo86@gmail.com.ORCID 0000-0003-3159-1678
D MantillaFrom the Neuroradiology Department (F.C., D.M., P.-H.L., C.D., G.G., C.R., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.ORCID 0000-0002-5727-3195
A RouchaudInterventional Neuroradiology NEURI Center (A.R.), Hôpital Bicêtre, Le Kremlin Bicêtre, France.ORCID 0000-0003-0902-3375
W BrinjikjiDepartment of Radiology (W.B.), Mayo Medical School, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-5271-5524
P-H LefevreFrom the Neuroradiology Department (F.C., D.M., P.-H.L., C.D., G.G., C.R., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.ORCID 0000-0002-6196-3869
C DargazanliFrom the Neuroradiology Department (F.C., D.M., P.-H.L., C.D., G.G., C.R., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.ORCID 0000-0003-1891-9157
G GascouFrom the Neuroradiology Department (F.C., D.M., P.-H.L., C.D., G.G., C.R., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.ORCID 0000-0002-0817-7324
C RiquelmeFrom the Neuroradiology Department (F.C., D.M., P.-H.L., C.D., G.G., C.R., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.ORCID 0000-0003-2070-6775
P PerriniDepartment of Neurosurgery (P.P., D.d.C.), University of Pisa, Pisa, Italy.ORCID 0000-0002-3251-6111
D di CarloDepartment of Neurosurgery (P.P., D.d.C.), University of Pisa, Pisa, Italy.ORCID 0000-0001-7136-4408
A BonafeFrom the Neuroradiology Department (F.C., D.M., P.-H.L., C.D., G.G., C.R., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.ORCID 0000-0002-9187-1375
V CostalatFrom the Neuroradiology Department (F.C., D.M., P.-H.L., C.D., G.G., C.R., A.B., V.C.), University Hospital Güi de Chauliac, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.ORCID 0000-0001-8428-9101
Hôpital Gui de Chauliac · FRUniversité de Montpellier · FRUniversity of Pisa · ITBicêtre Hospital · FRMayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe safety and efficacy of reconstructive and deconstructive endovascular treatments of very large/giant intracranial aneurysms are not completely clear. PURPOSE: Our aim was to compare treatment-related outcomes between these 2 techniques. DATA SOURCES: A systematic search of 3 data bases was performed for studies published from 1990 to 2017. STUDY SELECTION: We selected series of reconstructive and deconstructive treatments with >10 patients. DATA ANALYSIS: Random-effects meta-analysis was used to analyze occlusion rates, complications, and neurologic outcomes. DATA SYNTHESIS: Thirty-nine studies evaluating 894 very large/giant aneurysms were included. Long-term occlusion of unruptured aneurysms was 71% and 93% after reconstructive and deconstructive treatments, respectively ( LIMITATIONS: Limitations were selection and publication biases.

conclusionsParent artery occlusion allowed high rates of occlusion with an acceptable rate of complications for unruptured, anterior circulation aneurysms. Coiling should be preferred for posterior circulation and ruptured lesions, whereas flow diversion is relatively safe and effective for unruptured anterior circulation aneurysms.

Indexed as

AdultAgedEmbolization, TherapeuticEndovascular ProceduresFemaleHumansIntracranial AneurysmMalePlastic Surgery ProceduresStentsTreatment Outcome

Identifiers

PMID29545248
PMCPMC7410657
OpenAlexW2789906119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.