Evidence map›Paper›PMID 29545197›Full record

ArticleThe American journal of pathology2018

Induction of the Hajdu-Cheney Syndrome Mutation in CD19 B Cells in Mice Alters B-Cell Allocation but Not Skeletal Homeostasis.

Jungeun Yu, Stefano Zanotti, Lauren Schilling, Chris Schoenherr, Aris N Economides, Archana Sanjay, Ernesto Canalis

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Modulation of Notch1 signaling regulates bone fracture healing.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
  2. Review
  3. Notch in skeletal physiology and disease.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jungeun YuDepartment of Orthopaedic Surgery, UConn Health, Farmington, Connecticut; UConn Musculoskeletal Institute, UConn Health, Farmington, Connecticut.
Stefano ZanottiDepartment of Orthopaedic Surgery, UConn Health, Farmington, Connecticut; UConn Musculoskeletal Institute, UConn Health, Farmington, Connecticut; Department of Medicine, UConn Health, Farmington, Connecticut.
Lauren SchillingUConn Musculoskeletal Institute, UConn Health, Farmington, Connecticut.
Chris SchoenherrGenome Engineering Technologies, Regeneron Pharmaceuticals, Tarrytown, New York.
Aris N EconomidesGenome Engineering Technologies, Regeneron Pharmaceuticals, Tarrytown, New York.
Archana SanjayDepartment of Orthopaedic Surgery, UConn Health, Farmington, Connecticut; UConn Musculoskeletal Institute, UConn Health, Farmington, Connecticut. Electronic address: asanjay@uchc.edu.
Ernesto CanalisDepartment of Orthopaedic Surgery, UConn Health, Farmington, Connecticut; UConn Musculoskeletal Institute, UConn Health, Farmington, Connecticut; Department of Medicine, UConn Health, Farmington, Connecticut. Electronic address: canalis@uchc.edu.
UConn Health · USRegeneron (United States) · US

Funding

Mechanisms of Notch Action in BoneR01DK045227 · NIDDK · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CANALIS, ERNESTO · 1991 to 2018
$4.7M
Role of NFAT in the SkeletonR01AR068160 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CANALIS, ERNESTO · 2015 to 2019
$2.0M
Role of Notch Signaling in OsteocytesR01AR063049 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CANALIS, ERNESTO · 2013 to 2017
$1.8M
NIAMS NIH HHS R01 AR063049NIAMS NIH HHS R01 AR068160NIDDK NIH HHS R01 DK045227
6 · The paper itself

Abstract

Mice harboring Notch2 mutations replicating Hajdu-Cheney syndrome (Notch2

Indexed as

HomeostasisMutationAnimalsAntigens, CD19B-LymphocytesFemaleHajdu-Cheney SyndromeMaleMiceMice, Inbred C57BLMice, KnockoutMuscle, SkeletalReceptor, Notch2Antigens, CD19CD19 antigen, mouseNotch2 protein, mouseReceptor, Notch2

Identifiers

PMID29545197
PMCPMC5971225
OpenAlexW2789971676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.