ArticleMolecular brain2018
Superresolution fluorescence microscopy for 3D reconstruction of thick samples.
Article in Molecular brain, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Interferometric ultra-high resolution 3D imaging through brain sections.Nature communications · 2026Article
- Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Deep-Learning-Based Segmentation of Cells and Analysis (DL-SCAN).Biomolecules · 2024Article
- Extending the Depth of Focus of an Infrared Microscope Using a Binary Axicon Fabricated on Barium Fluoride.Micromachines · 2024Article
- Nontoxic Fluorescent Nanoprobes for Multiplexed Detection and 3D Imaging of Tumor Markers in Breast Cancer.Pharmaceutics · 2023Review
- Quantitative comparison of spinning disk geometries for PAINT based super-resolution microscopy.Biomedical optics express · 2022Article
- A single-molecule localization microscopy method for tissues reveals nonrandom nuclear pore distribution in Drosophila.Journal of cell science · 2021Article
- Three-Dimensional Single-Molecule Localization Microscopy in Whole-Cell and Tissue Specimens.Annual review of biomedical engineering · 2020Review
- Light Microscopy of Mitochondria at the Nanoscale.Annual review of biophysics · 2020Review
- Fluorescence imaging with tailored light.Nanophotonics (Berlin, Germany) · 2019Article
- Review
- Accelerated FRET-PAINT microscopy.Molecular brain · 2018Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 3 countries.
Funding
Abstract
Three-dimensional (3D) reconstruction of thick samples using superresolution fluorescence microscopy remains challenging due to high level of background noise and fast photobleaching of fluorescence probes. We develop superresolution fluorescence microscopy that can reconstruct 3D structures of thick samples with both high localization accuracy and no photobleaching problem. The background noise is reduced by optically sectioning the sample using line-scan confocal microscopy, and the photobleaching problem is overcome by using the DNA-PAINT (Point Accumulation for Imaging in Nanoscale Topography). As demonstrations, we take 3D superresolution images of microtubules of a whole cell, and two-color 3D images of microtubules and mitochondria. We also present superresolution images of chemical synapse of a mouse brain section at different z-positions ranging from 0 μm to 100 μm.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.