ArticleBMC gastroenterology2018
Recurrent common bile duct stones as a late complication of endoscopic sphincterotomy.
Article in BMC gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05896280 (Effects of Endoclip Papilloplasty and Relationship Between Post-operative Microecological Environment and Recurrent Bile Duct Stones), which is not on this map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Endoclip Papilloplasty and Relationship Between Post-operative Microecological Environment and Recurrent Bile Duct Stones
Who cites it
33 citing papers in PubMed, 76 citations in OpenAlex.
- Papillary Balloon Dilation Versus Sphincterotomy for Small Common Bile Duct Stones: Recurrence and Pneumobilia in a Retrospective Cohort.Digestive diseases and sciences · 2026Article
- Article
- Single-stage laparoendoscopic management of cholecystocholedocholithiasis: A retrospective study comparing starting with ERCP versus with laparoscopic cholecystectomy.Annals of hepato-biliary-pancreatic surgery · 2025Article
- Routine Nasobiliary Cholangiography After ERCP for Choledocholithiasis May Be Unnecessary: A Single-Center Retrospective Cohort Study.International journal of general medicine · 2025Article
- Characterization of biliary and duodenal microbiota in patients with primary and recurrent choledocholithiasis.Health information science and systems · 2024Article
- Recurrence of common bile duct stones after endoscopic clearance and its predictors: A systematic review.DEN open · 2024Review
- Risk factors for recurrence of common bile duct stones after surgical treatment and effect of ursodeoxycholic acid intervention.World journal of gastrointestinal surgery · 2024Article
- Comparative analysis of laparoscopic choledocholithiasis and ERCP treatment after cholecystectomy.BMC surgery · 2023Article
- Comparison Study between ERCP and PTBD for Recurrent Choledocholithiasis in Patients Following Gastrectomy.Diagnostics (Basel, Switzerland) · 2023Article
- Gas Embolism After a Patient's Ninth ERCP Procedure.ACG case reports journal · 2023Article
- Predicting the Recurrence of Common Bile Duct Stones After ERCP Treatment with Automated Machine Learning Algorithms.Digestive diseases and sciences · 2023Article
- Primary suture for patients of bile duct stones after laparoscopic biliary tract exploration: a retrospective cohort study.Updates in surgery · 2023Article
- Surgical application of an implantable biliary access device in the treatment of refractory recurrent cholangiolithiasis.Quantitative imaging in medicine and surgery · 2023Article
- Primary Recurrent Common Bile Duct Stones: Timing of Surgical Intervention.Journal of clinical medicine research · 2022Review
- Bile Microbiome in Patients with Recurrent Common Bile Duct Stones and Correlation with the Duodenal Microbiome.Life (Basel, Switzerland) · 2022Article
- The safety and feasibility of laparoscopic approach for the management of intrahepatic and extrahepatic bile duct stones in patients with prior biliary tract surgical interventions.Scientific reports · 2022Article
- A nomogram for predicting stones recurrence in patients with bile duct stones undergoing laparoscopic common bile duct exploration.Annals of gastroenterological surgery · 2022Article
- Predictors for stone recurrence after a successful common bile duct surgical exploration for choledocholithiasis.Langenbeck's archives of surgery · 2022Article
- Microbiota analysis with next-generation 16S rDNA gene sequencing in recurrent common bile duct stones.Annals of translational medicine · 2022Article
- Low insertion of cystic duct increases risk for common bile duct stone recurrence.Surgical endoscopy · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundEndoscopic retrograde cholangiopancreatography (ERCP) with endoscopic sphincterotomy (ES) has become well established as a modality for the management of common bile duct stones (CBDS), especially in the setting of associated cholangitis. Our study aims to determine the rate of long term morbidity of recurrent CBDS post ES.
methodsA retrospective analysis of patients who underwent ERCP and ES (ERCP+ES) was undertaken on a prospectively maintained database from 1998 to 2012 at the Northern Hospital, Melbourne. Primary CBDS were defined as those detected at least 6 months after complete clearance of the CBD. Prior cholecystectomy was a requirement for inclusion and patients with primary CBD stones in the setting of an intact sphincter were excluded.
resultsA total of 1148 patients underwent ERCP, of which 573 had an ES. Fifty-one patients underwent an ES prior to developing primary CBDS (8.9%). The time to recurrence ranged from 6 months to 15 years (mean 3.3 years). The number of procedures per patient ranged from 2 to 11, with 51% requiring 3 or more ERCPs. Factors associated with primary CBDS recurrence included a dilated CBD > 12 mm, stricture of the major papilla post ES to 2 - 5 mm and presence of the ampulla within or on the edge of a duodenal diverticulum.
conclusionThe results demonstrate that ERCP + ES has an inherent long-term complication of recurrent primary CBDS formation. While this can be managed with repeat ERCP, the advent of laparoscopic bile duct exploration should lead us to re-examine the role of ERCP + ES in younger patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.