Evidence map›Paper›PMID 29544424›Full record

ArticleWorld journal for pediatric & congenital heart surgery2018

Association of Habitual Activity and Body Mass Index in Survivors of Congenital Heart Surgery: A Study of Children and Adolescents With Tetralogy of Fallot, Transposition of the Great Arteries, and Fontan Palliation.

Michael L O'Byrne, Michael G McBride, Stephen Paridon, Elizabeth Goldmuntz

Open access · greenAbstract read
In one paragraph

Article in World journal for pediatric & congenital heart surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Overweight and Obesity in Patients with Congenital Heart Disease: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. The Cardiovascular Care of the Pediatric Athlete.Journal of the American College of Cardiology · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Body Mass Index Trajectory and Outcome Post Fontan Procedure.Journal of the American Heart Association · 2022
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michael L O'Byrne1 Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Michael G McBride1 Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Stephen Paridon1 Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Elizabeth Goldmuntz1 Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
University of Pennsylvania · USChildren's Hospital of Philadelphia · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
Molecular Analysis of Human Subtelomeric RearrangementsP50HL074731 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI KRANTZ, IAN D. · 2004 to 2008
$19.2M
Training in Molecular Therapeutics for Pediatric CardiologyT32HL007915 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI Robert J Levy, JOSEPH W ROSSANO · 1999 to 2026
$13.4M
Outcomes in Children Undergoing Cardiac CatheterizationK23HL130420 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI O'BYRNE, MICHAEL L · 2016 to 2020
$907k
NHLBI NIH HHS K23 HL130420NHLBI NIH HHS P50 HL074731NHLBI NIH HHS T32 HL007915
6 · The paper itself

Abstract

backgroundObesity is associated with increased lifelong morbidity and reduced life span and is increasingly prevalent in the congenital heart disease population. Habitual exercise is an important aspect of a healthy lifestyle and primary prevention of obesity in the general population. The association between habitual activity and body mass index (BMI) has not been studied in children with congenital heart disease.

methodsA cross-sectional analysis of two previously collected cohorts was performed, including participants 8 to 18 years old with tetralogy of Fallot, transposition of the great arteries, and single ventricle heart disease after a Fontan operation. The association between BMI and duration of habitual exercise (measured by questionnaire) was studied. Secondary analyses assessing the effect of other possible factors for BMI were performed.

resultsIn total, 172 participants were studied (45% Tetralogy of Fallot, 12% transposition of the great arteries, and 43% Fontan). Median BMI was 18.2, and 29% of the participants were obese or overweight. Median habitual exercise was 5.9 h/wk. Thirty-eight percent of participants reported having their activity restricted by their cardiologist. Increasing exercise duration was associated with lower BMI ( P = .01) in univariate analysis. In secondary analyses, restriction to mild exertion and participation in low-intensity exercise were both associated with increased BMI.

conclusionIncreased habitual activity was associated with lower BMI, emphasizing the potential role of recreational sport in the health of children with congenital heart disease.

Indexed as

Body Mass IndexExerciseFontan ProcedureAdolescentChildCross-Sectional StudiesFemaleHealth BehaviorHumansMalePediatric ObesityPostoperative ComplicationsRetrospective StudiesRisk FactorsSurveys and QuestionnairesTetralogy of Fallotexercise physiologyhypoplastic left heart syndromeoutcomes researchpediatric cardiologytransposition of the great arteries

Identifiers

PMID29544424
PMCPMC6154798
OpenAlexW2793512452

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.