Evidence map›Paper›PMID 29543910›Full record

ArticlePLoS neglected tropical diseases2018

Spatio-temporal coherence of dengue, chikungunya and Zika outbreaks in Merida, Mexico.

Donal Bisanzio, Felipe Dzul-Manzanilla, Hector Gomez-Dantés, Norma Pavia-Ruz, Thomas J Hladish, Audrey Lenhart, Jorge Palacio-Vargas, Jesus F González Roldan, Fabian Correa-Morales, Gustavo Sánchez-Tejeda and 5 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Effect of Socioeconomic Strata and Land Cover on Dengue Hotspots in Medellin, Colombia.The American journal of tropical medicine and hygiene · 2025
    Article
  9. Role of Non-Residential Larval Habitats inLife (Basel, Switzerland) · 2024
    Article
  10. Evidence of Ongoing Transmission of Zika Virus in Mérida, Mexico.The American journal of tropical medicine and hygiene · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Donal BisanzioRTI International, Washington, DC, United States of America.ORCID 0000-0002-7832-2291
Felipe Dzul-ManzanillaCentro Nacional de Programas Preventivos y Control de Enfermedades (CENAPRECE) Secretaría de Salud Mexico, Mexico City, Mexico.ORCID 0000-0002-2085-9141
Hector Gomez-DantésHealth Systems Research Center, National Institute of Public Health, Cuernavaca, Mexico.
Norma Pavia-RuzCentro de Investigaciones Regionales Hideyo Noguchi, Universidad Autonoma de Yucatan, Merida, Mexico.
Thomas J HladishDepartment of Biology, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0003-1819-6235
Audrey LenhartCenters for Disease Control and Prevention, Atlanta, GA, United States of America.
Jorge Palacio-VargasSecretaria de Salud de Yucatan. Merida, Mexico.
Jesus F González RoldanCentro Nacional de Programas Preventivos y Control de Enfermedades (CENAPRECE) Secretaría de Salud Mexico, Mexico City, Mexico.
Fabian Correa-MoralesCentro Nacional de Programas Preventivos y Control de Enfermedades (CENAPRECE) Secretaría de Salud Mexico, Mexico City, Mexico.
Gustavo Sánchez-TejedaCentro Nacional de Programas Preventivos y Control de Enfermedades (CENAPRECE) Secretaría de Salud Mexico, Mexico City, Mexico.
Pablo Kuri MoralesSubsecretaría de Prevención y Promoción de la Salud, Mexico City, Mexico.
Pablo Manrique-SaideUnidad Colaborativa de Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Merida, Mexico.
Ira M LonginiEmerging Pathogens Institute, University of Florida, Gainesville, FL, United States of America.
M Elizabeth HalloranCenter for Inference and Dynamics of Infectious Diseases, Seattle, WA, United States of America.
Gonzalo M Vazquez-ProkopecDepartment of Environmental Sciences, Emory University, Atlanta, GA, United States of America.

Funding

Understanding Transmission with Integrated Genetic and Epidemiologic InferenceU54GM111274 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VESPIGNANI, ALESSANDRO · 2014 to 2018
$12.5M
NIGMS NIH HHS U54 GM111274
6 · The paper itself

Abstract

Response to Zika virus (ZIKV) invasion in Brazil lagged a year from its estimated February 2014 introduction, and was triggered by the occurrence of severe congenital malformations. Dengue (DENV) and chikungunya (CHIKV) invasions tend to show similar response lags. We analyzed geo-coded symptomatic case reports from the city of Merida, Mexico, with the goal of assessing the utility of historical DENV data to infer CHIKV and ZIKV introduction and propagation. About 42% of the 40,028 DENV cases reported during 2008-2015 clustered in 27% of the city, and these clustering areas were where the first CHIKV and ZIKV cases were reported in 2015 and 2016, respectively. Furthermore, the three viruses had significant agreement in their spatio-temporal distribution (Kendall W>0.63; p<0.01). Longitudinal DENV data generated patterns indicative of the resulting introduction and transmission patterns of CHIKV and ZIKV, leading to important insights for the surveillance and targeted control to emerging Aedes-borne viruses.

Indexed as

Disease OutbreaksAedesAnimalsChikungunya FeverChikungunya virusDengueDengue VirusGeographic MappingHumansMexicoMosquito ControlMosquito VectorsSpatio-Temporal AnalysisZika VirusZika Virus Infection

Identifiers

PMID29543910
PMCPMC5870998

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.