Evidence map›Paper›PMID 29543781›Full record

ArticleNutrients2018

Chondroprotective Effects of a Standardized Extract (KBH-JP-040) from Kalopanax pictus, Hericium erinaceus, and Astragalus membranaceus in Experimentally Induced In Vitro and In Vivo Osteoarthritis Models.

Md Mahbubur Rahman, Hyun-Kyu Kim, Seong-Eun Kim, Myung-Jin Kim, Do-Hyung Kim, Hak Sung Lee

Open access · goldAbstract readComparative Study
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Efficacy and Mechanisms ofCurrent rheumatology reviews · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Lion's Mane Mushroom (Nutrients · 2025
    Review
  6. Nutrients · 2022
    Article
  7. Immune-Enhancing Effects of Co-treatment WithFrontiers in nutrition · 2022
    Article
  8. Article
  9. Chemical Discrimination ofMolecules (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Md Mahbubur RahmanKNOTUS Co., Ltd. Research and Development Center, 189 Donggureung-Ro, Guri-Si 11910, Gyeonggi-Do, Korea. mahbub@knotus.co.kr.
Hyun-Kyu KimKolmar BNH Co., Ltd. 22-15, Sandan-gil, Jeonui-myeon, Sejong-si 30003, Korea. hkkim@kolmarbnh.co.kr.
Seong-Eun KimKolmar BNH Co., Ltd. 22-15, Sandan-gil, Jeonui-myeon, Sejong-si 30003, Korea. kse1316@kolmarbnh.co.kr.
Myung-Jin KimKNOTUS Co., Ltd. Research and Development Center, 189 Donggureung-Ro, Guri-Si 11910, Gyeonggi-Do, Korea. third_onezest@knotus.co.kr.
Do-Hyung KimKNOTUS Co., Ltd. Research and Development Center, 189 Donggureung-Ro, Guri-Si 11910, Gyeonggi-Do, Korea. lab@knotus.co.kr.
Hak Sung LeeKolmar BNH Co., Ltd. 22-15, Sandan-gil, Jeonui-myeon, Sejong-si 30003, Korea. mildpeople@kolmarbnh.co.kr.ORCID 0000-0001-9594-7173
Kolmar Korea (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the chondroprotective effect of a standardized extract (KBH-JP-040) of the Korean traditional herbs

Indexed as

Astragalus propinquusBasidiomycotaKalopanaxAnimalsAnti-Inflammatory AgentsArthritis, ExperimentalCelecoxibCells, CulturedChondrocytesCollagenCollagenasesCytokinesDose-Response Relationship, DrugInflammation MediatorsInterleukin-1betaJointsAnti-Inflammatory AgentsCelecoxibCollagenCollagenasesCytokinesIL1B protein, humanInflammation MediatorsInterleukin-1betaKBH-JP-040Matrix MetalloproteinasesPlant ExtractsReactive Oxygen SpeciesarthritisAstragalus membranaceuschondrocytesHericium erinaceusKalopanax pictus

Identifiers

PMID29543781
PMCPMC5872774
OpenAlexW2791105175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.