Evidence map›Paper›PMID 29543583›Full record

ArticleHuman vaccines & immunotherapeutics2018

Late onset of injection site reactions after vaccination with the 13-valent pneumococcal conjugate vaccine in adult study populations.

Christine Juergens, James Trammel, Yasuko Shoji, Scott Patterson, Wendy Watson, Chris Webber, William C Gruber, Daniel A Scott, Beate Schmoele-Thoma

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Christine Juergensa Pfizer Vaccine Clinical Research and Development , Pfizer Pharma GmbH , Berlin , Germany.
James Trammelb Biostatistics, Syneos Health , Stonewall , LA , USA.
Yasuko Shojic Pfizer Vaccine Clinical Research and Development , Tokyo , Japan.
Scott Pattersond Pfizer Vaccines Clinical Research & Development , Collegeville , PA , USA.
Wendy Watsond Pfizer Vaccines Clinical Research & Development , Collegeville , PA , USA.
Chris Webbere Pfizer Vaccines Clinical Research & Development , Pearl River , NY , USA.
William C Grubere Pfizer Vaccines Clinical Research & Development , Pearl River , NY , USA.
Daniel A Scottd Pfizer Vaccines Clinical Research & Development , Collegeville , PA , USA.
Beate Schmoele-Thomaa Pfizer Vaccine Clinical Research and Development , Pfizer Pharma GmbH , Berlin , Germany.ORCID 0000-0003-4632-357X
Pfizer (United States) · USPfizer (Germany) · DEPfizer (Japan) · JPSyneos Health (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injection site reactions (ISRs; redness, swelling and pain) commonly occur within 1-2 days after vaccination. After administration of toxoid vaccines including diphtheria toxoid, a later onset of ISRs has also been observed. As the serotype capsular polysaccharides in the 13-valent pneumococcal conjugate vaccine (PCV13) are conjugated to cross-reactive material 197 (CRM

Indexed as

Adjuvants, ImmunologicAdultAgedAge FactorsAluminum CompoundsBacterial ProteinsClinical Studies as TopicCohort StudiesHumansImmunization, SecondaryIncidenceInjection Site ReactionMass VaccinationMiddle AgedPhosphatesPneumococcal Infections13-valent pneumococcal vaccine23-valent pneumococcal capsular polysaccharide vaccineAdjuvants, ImmunologicAluminum Compoundsaluminum phosphateBacterial ProteinsCRM197 (non-toxic variant of diphtheria toxin)PhosphatesPneumococcal VaccinesVaccines, Conjugate13-valent pneumococcal conjugate vaccineadultslate injection site reactionssafetyvaccination

Identifiers

PMID29543583
PMCPMC6149808
OpenAlexW2789290712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.