Evidence map›Paper›PMID 29543531›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2018

Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis.

Corinna Schmitz, Heidi Noels, Omar El Bounkari, Eva Straussfeld, Remco T A Megens, Marieke Sternkopf, Setareh Alampour-Rajabi, Christine Krammer, Pathricia V Tilstam, Norbert Gerdes and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  7. The role of CD74 in cardiovascular disease.Frontiers in cardiovascular medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 3 countries.

Corinna SchmitzVascular Biology, Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Heidi NoelsInstitute for Molecular Cardiovascular Research (IMCAR), University Hospital Aachen, Rheinish-Westphalian Technical University (RWTH) Aachen University, Aachen, Germany.
Omar El BounkariVascular Biology, Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Eva StraussfeldVascular Biology, Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Remco T A MegensInstitute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Marieke SternkopfInstitute for Molecular Cardiovascular Research (IMCAR), University Hospital Aachen, Rheinish-Westphalian Technical University (RWTH) Aachen University, Aachen, Germany.
Setareh Alampour-RajabiInstitute for Molecular Cardiovascular Research (IMCAR), University Hospital Aachen, Rheinish-Westphalian Technical University (RWTH) Aachen University, Aachen, Germany.
Christine KrammerVascular Biology, Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Pathricia V TilstamInstitute for Molecular Cardiovascular Research (IMCAR), University Hospital Aachen, Rheinish-Westphalian Technical University (RWTH) Aachen University, Aachen, Germany.
Norbert GerdesInstitute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Christina BürgerInstitute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Aphrodite KapurniotuDivision of Peptide Biochemistry, Technische Universität München, Freising, Germany.
Richard BucalaYale School of Medicine, Yale University, New Haven, Connecticut, USA.
Joachim JankowskiInstitute for Molecular Cardiovascular Research (IMCAR), University Hospital Aachen, Rheinish-Westphalian Technical University (RWTH) Aachen University, Aachen, Germany.
Christian WeberInstitute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Jürgen BernhagenVascular Biology, Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.
Ludwig-Maximilians-Universität München · DEUniversitätsklinikum Aachen · DEMaastricht University · NLYale University · USDüsseldorf University Hospital · DERWTH Aachen University · DETechnical University of Munich · DE

Funding

Yale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI YASUKO IWAKIRI · 1986 to 2026
$31.1M
Mechanisms of Rheumatoid Synovial Fibroblast ActivationR01AR049610 · NIAMS · YALE UNIVERSITY · PI BUCALA, RICHARD J · 2002 to 2018
$5.0M
NIAMS NIH HHS R01 AR049610NIDDK NIH HHS P30 DK034989
6 · The paper itself

Abstract

The inflammatory cytokine macrophage migration-inhibitory factor (MIF) promotes atherosclerosis via lesional monocyte and T-cell recruitment. B cells have emerged as important components in atherogenesis, but the interaction between MIF and B cells in atherogenesis is unknown. Here, we investigated the atherosclerotic phenotype of Mif-gene deletion in Apoe

Indexed as

AnimalsAortaApolipoproteins EAtherosclerosisAutoantibodiesB-LymphocytesCell DifferentiationFemaleIntramolecular OxidoreductasesLipoproteins, LDLMacrophage Migration-Inhibitory FactorsMaleMiceMice, Inbred C57BLMonocytesPhenotypeApolipoproteins EAutoantibodiesIntramolecular OxidoreductasesLipoproteins, LDLMacrophage Migration-Inhibitory FactorsMif protein, mouseoxidized low density lipoproteinantibodychemokineimmunologylymphocyte

Identifiers

PMID29543531
PMCPMC6207164
OpenAlexW2792243645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.