Evidence map›Paper›PMID 29542846›Full record

ArticleAngewandte Chemie (International ed. in English)2018

Strain-Promoted Cycloaddition of Cyclopropenes with o-Quinones: A Rapid Click Reaction.

Digvijay Gahtory, Rickdeb Sen, Andriy R Kuzmyn, Jorge Escorihuela, Han Zuilhof

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Exploring Scent Distinction with Polymer Brush Arrays.ACS applied polymer materials · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cycloaddition of Strained Cyclic Alkenes andThe Journal of organic chemistry · 2020
    Article
  13. Review
  14. Article
  15. Antifouling Polymer Brushes via Oxygen-Tolerant Surface-Initiated PET-RAFT.Langmuir : the ACS journal of surfaces and colloids · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Digvijay GahtoryLaboratory of Organic Chemistry, Wageningen University and Research, Stippeneng 4, 6708, WE, Wageningen, The Netherlands.ORCID 0000-0002-7599-1684
Rickdeb SenLaboratory of Organic Chemistry, Wageningen University and Research, Stippeneng 4, 6708, WE, Wageningen, The Netherlands.ORCID 0000-0003-1735-9071
Andriy R KuzmynLaboratory of Organic Chemistry, Wageningen University and Research, Stippeneng 4, 6708, WE, Wageningen, The Netherlands.ORCID 0000-0002-1571-2911
Jorge EscorihuelaDepartamento de Química Orgánica, Facultad de Química, Universidad de Valencia, Avda. Vicente Andrés Estellés s.n., 46100-Burjassot, Valencia, Spain.ORCID 0000-0001-6756-0991
Han ZuilhofLaboratory of Organic Chemistry, Wageningen University and Research, Stippeneng 4, 6708, WE, Wageningen, The Netherlands.ORCID 0000-0001-5773-8506

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel click reactions are of continued interest in fields as diverse as bio-conjugation, polymer science and surface chemistry. Qualification as a proper "click" reaction requires stringent criteria, including fast kinetics and high conversion, to be met. Herein, we report a novel strain-promoted cycloaddition between cyclopropenes and o-quinones in solution and on a surface. We demonstrate the "click character" of the reaction in solution and on surfaces for both monolayer and polymer brush functionalization.

Indexed as

kineticsmass spectrometrymetal-free click reactionsmonolayerspolymer brushes

Identifiers

PMID29542846
PMCPMC6099469

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.