Evidence map›Paper›PMID 29542821›Full record

ArticleMedical physics2018

Reduced anatomical clutter in digital breast tomosynthesis with statistical iterative reconstruction.

John W Garrett, Yinsheng Li, Ke Li, Guang-Hong Chen

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. [Assessment of imaging performance of digital breast tomosynthesis based on systematic simulation].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Imaging of fiber-like structures in digital breast tomosynthesis.Journal of medical imaging (Bellingham, Wash.) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

John W GarrettDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Yinsheng LiDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Ke LiDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Guang-Hong ChenDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
University of Wisconsin–Madison · US

Funding

Multi-Contrast X-ray Breast ImagingR01EB020521 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI CHEN, GUANG-HONG, LI, KE · 2016 to 2020
$2.0M
NIBIB NIH HHS R01 EB020521
6 · The paper itself

Abstract

purposeDigital breast tomosynthesis (DBT) has been shown to somewhat alleviate the breast tissue overlapping issues of two-dimensional (2D) mammography. However, the improvement in current DBT systems over mammography is still limited. Statistical image reconstruction (SIR) methods have the potential to reduce through-plane artifacts in DBT, and thus may be used to further reduce anatomical clutter. The purpose of this work was to study the impact of SIR on anatomical clutter in the reconstructed DBT image volumes.

methodsAn SIR with a slice-wise total variation (TV) regularizer was implemented to reconstruct DBT images which were compared with the clinical reconstruction method (filtered backprojection). The artifact spread function (ASF) was measured to quantify the reduction of the through-plane artifacts level in phantom studies and microcalcifications in clinical cases. The anatomical clutter was quantified by the anatomical noise power spectrum with a power law fitting model: NPS

resultsThe full width half maximum (FWHM) of the measured ASF was reduced from 8.7 ± 0.1 mm for clinical reconstruction to 6.5 ± 0.1 mm for SIR which yields a 25% reduction in FWHM in phantom studies and the same amount of ASF reduction was also found in clinical measurements from microcalcifications. The measured β values for the two reconstruction methods were 3.17 ± 0.36 and 2.14 ± 0.39 for the clinical reconstruction method and the SIR method, respectively. This difference was statistically significant (P << 0.001). The dependence of β on slice location using either method was negligible.

conclusionsStatistical image reconstruction enabled a significant reduction of both the through-plane artifacts level and anatomical clutter in the DBT reconstructions. The β value was found to be β≈2.14 with the SIR method. This value stays in the middle between the β≈1.8 for cone beam CT and β≈3.2 for mammography. In contrast, the measured β value in the clinical reconstructions (β≈3.17) remains close to that of mammography.

Indexed as

MammographyStatistics as TopicAlgorithmsArtifactsBreastImage Processing, Computer-Assistedanatomical clutteranatomical noisebreast cancerbreast imagingDBTdigital breast tomosynthesisiterative reconstruction

Identifiers

PMID29542821
PMCPMC8697636
OpenAlexW2790308029

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.