ArticleNature2018
High-resolution magnetic resonance spectroscopy using a solid-state spin sensor.
Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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Who cites it
71 citing papers in PubMed, 422 citations in OpenAlex.
- Multimodal scanning-probe quantum sensing of quantum materials.Nature materials · 2026Review
- Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO-Chitosan Biointerfaces.Advanced healthcare materials · 2026Article
- Magnetometry for Agriculture and Animal Systems: From Classical Sensors to Quantum-Enabled Biosensing.Biosensors · 2026Review
- Readout of a solid state spin ensemble at the projection noise limit.Nature communications · 2026Article
- Experimental observation of liquid-solid transition of nanoconfined water at ambient temperature.Nature materials · 2026Article
- Chemically Resolved Nuclear Magnetic Resonance Spectroscopy by Longitudinal Magnetization Detection with a Diamond Magnetometer.ACS measurement science au · 2026Article
- Device engineering for photocurrent detected magnetic resonance and scanning probes using solid-state spin defects.Science and technology of advanced materials · 2026Review
- Quantum sensing with spin defects in boron nitride nanotubes.Nature communications · 2025Article
- Formation of luminescent defects in 4H-SiC upon ion irradiation and ns laser annealing.Scientific reports · 2025Article
- Pulse sequence design for high field NMR with NV centers in dipolarly coupled samples.Scientific reports · 2025Article
- High-Resolution Nanoscale AC Quantum Sensing in CMOS Compatible SiC.Nano letters · 2025Article
- Microwave quantum heterodyne sensing using a continuous concatenated dynamical decoupling protocol.Nature communications · 2025Article
- Single cobalt atoms with unconventional dynamic coordination mechanism for selective ammonia sensor.National science review · 2025Article
- Solid-state spin coherence time approaching the physical limit.Science advances · 2025Article
- Optical widefield nuclear magnetic resonance microscopy.Nature communications · 2025Article
- Quantum magnetometry of transient signals with a time resolution of 1.1 nanoseconds.Nature communications · 2025Article
- High-precision chemical quantum sensing in flowing monodisperse microdroplets.Science advances · 2024Article
- Quantum sensing with optically accessible spin defects in van der Waals layered materials.Light, science & applications · 2024Article
- Direct-bonded diamond membranes for heterogeneous quantum and electronic technologies.Nature communications · 2024Article
- High-Q cavity interface for color centers in thin film diamond.Nature communications · 2024Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quantum systems that consist of solid-state electronic spins can be sensitive detectors of nuclear magnetic resonance (NMR) signals, particularly from very small samples. For example, nitrogen-vacancy centres in diamond have been used to record NMR signals from nanometre-scale samples, with sensitivity sufficient to detect the magnetic field produced by a single protein. However, the best reported spectral resolution for NMR of molecules using nitrogen-vacancy centres is about 100 hertz. This is insufficient to resolve the key spectral identifiers of molecular structure that are critical to NMR applications in chemistry, structural biology and materials research, such as scalar couplings (which require a resolution of less than ten hertz) and small chemical shifts (which require a resolution of around one part per million of the nuclear Larmor frequency). Conventional, inductively detected NMR can provide the necessary high spectral resolution, but its limited sensitivity typically requires millimetre-scale samples, precluding applications that involve smaller samples, such as picolitre-volume chemical analysis or correlated optical and NMR microscopy. Here we demonstrate a measurement technique that uses a solid-state spin sensor (a magnetometer) consisting of an ensemble of nitrogen-vacancy centres in combination with a narrowband synchronized readout protocol to obtain NMR spectral resolution of about one hertz. We use this technique to observe NMR scalar couplings in a micrometre-scale sample volume of approximately ten picolitres. We also use the ensemble of nitrogen-vacancy centres to apply NMR to thermally polarized nuclear spins and resolve chemical-shift spectra from small molecules. Our technique enables analytical NMR spectroscopy at the scale of single cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.