Evidence map›Paper›PMID 29542262›Full record

Trial reportHead & neck2018

Pilot randomized controlled trial of a comprehensive smoking cessation intervention for patients with upper aerodigestive cancer undergoing radiotherapy.

Eleni M Rettig, Carole Fakhry, Russell K Hales, Flora Kisuule, Harry Quon, Ana P Kiess, Linda X Yin, Yuehan Zhang, Amanda L Blackford, M Bradley Drummond and 4 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Head & neck, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 7 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 7 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Incentives for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  5. Systematic Review of Smoking Cessation Interventions for Smokers Diagnosed with Cancer.International journal of environmental research and public health · 2022
    Pooled it
  6. Incentives for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  7. Interventions for smoking cessation in people diagnosed with lung cancer.The Cochrane database of systematic reviews · 2019
    Pooled it
  8. A Preoperative Contingency Management Intervention for Smoking Abstinence in Cancer Patients: A Preliminary Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Trial
  9. Observational
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Eleni M RettigDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-4715-0087
Carole FakhryDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Russell K HalesDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Flora KisuuleDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Harry QuonDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ana P KiessDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Linda X YinDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Yuehan ZhangDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Amanda L BlackfordDepartment of Oncology, Division of Biostatistics and Bioinformatics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
M Bradley DrummondDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Christine G GourinDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Wayne M KochDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
David W EiseleDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Gypsyamber D'SouzaDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Johns Hopkins University · US

Funding

RESEARCH TRAINING IN OTOLARYNGOLOGYT32DC000027 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI CAREY, JOHN PATRICK · 1989 to 2023
$5.5M
NIDCD NIH HHS T32 DC000027
6 · The paper itself

Abstract

backgroundSmoking among patients with cancer is associated with poor outcomes, however, smoking cessation interventions have had limited success.

methodsThis randomized controlled trial compared a novel smoking cessation intervention ("intervention") with enhanced usual care ("control"). Participants were smokers with head and neck or thoracic malignancies undergoing radiation. Controls received brief counseling. Intervention participants received intensive counseling, pharmacotherapy, text-messaging, and financial incentives. Biochemically confirmed 7-day abstinence at 8 weeks was compared using Fisher's exact t test. Smoking abstinence and intensity were also analyzed using time-series panel regression.

resultsThe study population comprised 19 intervention and 10 control participants. More intervention (74%) than control (30%) participants abstained from smoking at 8 weeks (P = .05). Intervention participants were significantly more likely to abstain (adjusted odds ratio [OR] 14.70; 95% confidence interval [CI] 3.56-60.76) and smoked fewer cigarettes (adjusted incidence rate ratio [IRR], 0.16; 95% CI 0.06-0.40) during weeks 1 to 8.

conclusionThis intervention decreased smoking among patients with upper aerodigestive cancers during radiotherapy.

Indexed as

CounselingFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedPilot ProjectsProgram EvaluationSmoking CessationText MessagingThoracic NeoplasmsTobacco Use Cessation Deviceshead and neck cancerlung cancerradiotherapysmoking cessation interventiontobacco dependence

Identifiers

PMID29542262
PMCPMC6037556
OpenAlexW2793945258

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.