Evidence map›Paper›PMID 29542260›Full record

ArticleJournal of applied clinical medical physics2018

Comparative analysis for renal stereotactic body radiotherapy using Cyberknife, VMAT and proton therapy based treatment planning.

Atallah Baydoun, Neha Vapiwala, Lee E Ponsky, Musaddiq Awan, Ali Kassaee, David Sutton, Tarun K Podder, Yuxia Zhang, Donald Dobbins, Raymond F Muzic and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Atallah BaydounDepartment of Internal Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Neha VapiwalaAbramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
Lee E PonskyDepartment of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Musaddiq AwanDepartment of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Ali KassaeeDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA.
David SuttonDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA.
Tarun K PodderDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.
Yuxia ZhangDepartment of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Donald DobbinsDepartment of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Raymond F MuzicDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.
Bryan TraughberDepartment of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Mitchell MachtayDepartment of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Rodney EllisDepartment of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Case Western Reserve University · USUniversity Hospitals Seidman Cancer Center · USUniversity of Pennsylvania · USUniversity School · USUniversity Hospitals Case Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe conducted this dosimetric analysis to evaluate the feasibility of a multi-center stereotactic body radiation therapy (SBRT) trial for renal cell carcinoma (RCC) using different SBRT platforms. MATERIALS/

methodsThe computed tomography (CT) simulation images of 10 patients with unilateral RCC previously treated on a Phase 1 trial at Institution 1 were anonymized and shared with Institution 2 after IRB approval. Treatment planning was generated through five different platforms aiming a total dose of 48 Gy in three fractions. These platforms included: Cyberknife and volumetric modulated arc therapy (VMAT) at institution 1, and Cyberknife, VMAT, and pencil beam scanning (PBS) Proton Therapy at institution 2. Dose constraints were based on the Phase 1 approved trial.

resultsCompared to Cyberknife, VMAT and PBS plans provided overall an equivalent or superior coverage to the target volume, while limiting dose to the remaining kidney, contralateral kidney, liver, spinal cord, and bowel.

conclusionThis dosimetric study supports the feasibility of a multi-center trial for renal SBRT using PBS, VMAT and Cyberknife.

Indexed as

proton therapyrenal cell carcinomaSBRTVMAT

Identifiers

PMID29542260
PMCPMC5978559
OpenAlexW2792057816

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.