Evidence map›Paper›PMID 29541889›Full record

ArticleEcotoxicology (London, England)2018

The psychoactive drug Escitalopram affects swimming behaviour and increases boldness in zebrafish (Danio rerio).

Sebastian V Nielsen, Martin Kellner, Per G Henriksen, Håkan Olsén, Steen H Hansen, Erik Baatrup

Abstract read
PubMed Publisher
In one paragraph

Article in Ecotoxicology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sebastian V NielsenDepartment of Bioscience, Zoophysiology, Aarhus University, CF Moellersalle 3, building 1131, Aarhus C, Aarhus, DK-8000, Denmark.
Martin KellnerNatural Science, Technology and Environmental Studies, Södertörn University, Huddinge, S-141 89, Sweden.
Per G HenriksenDepartment of Bioscience, Zoophysiology, Aarhus University, CF Moellersalle 3, building 1131, Aarhus C, Aarhus, DK-8000, Denmark.
Håkan OlsénNatural Science, Technology and Environmental Studies, Södertörn University, Huddinge, S-141 89, Sweden.
Steen H HansenDepartment of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen, DK-2100, Denmark.
Erik BaatrupDepartment of Bioscience, Zoophysiology, Aarhus University, CF Moellersalle 3, building 1131, Aarhus C, Aarhus, DK-8000, Denmark. baatrup@bios.au.dk.
Aarhus University · DKSödertörn University · SEUniversity of Copenhagen · DK

Funding

Naturvidenskab og Teknologi, Aarhus Universitet 13025
6 · The paper itself

Abstract

Selective serotonin re-uptake inhibitors are pharmaceuticals used to treat a range of psychological disorders. They are frequently found in surface waters in populated areas. In recent years, they have been shown to affect the behaviour of various aquatic organisms in a way that can have ecological effects. In this study, we exposed zebrafish of both sexes to nominally 0.00, 0.15 and 1.50 µg L

Indexed as

AnimalsCitalopramDose-Response Relationship, DrugExploratory BehaviorFemaleMaleRandom AllocationSelective Serotonin Reuptake InhibitorsSex FactorsSwimmingWater Pollutants, ChemicalZebrafishCitalopramSelective Serotonin Reuptake InhibitorsWater Pollutants, ChemicalAltered swimming behaviourEscitalopramIncreased boldnessPsychoactive drugSSRIZebrafish

Identifiers

PMID29541889
OpenAlexW2794055127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.