Evidence map›Paper›PMID 29541861›Full record

ArticlePflugers Archiv : European journal of physiology2018

Internalization of NKCC2 is impaired in thick ascending limb of Henle in moesin knockout mice.

Kotoku Kawaguchi, Ryo Hatano, Mitsunobu Matsubara, Shinji Asano

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Molecular regulation of NKCC2 in blood pressure control and hypertension.Current opinion in nephrology and hypertension · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kotoku KawaguchiDepartment of Molecular Physiology, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1Noji Higashi, Kusatsu City, Shiga, 525-8577, Japan.
Ryo HatanoDepartment of Molecular Physiology, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1Noji Higashi, Kusatsu City, Shiga, 525-8577, Japan. hatanori@fc.ritsumei.ac.jp.ORCID 0000-0002-6833-829X
Mitsunobu MatsubaraDivision of Molecular Medicine, Center for Translational and Advanced Animal Research, Tohoku University Graduate School of Medicine, Sendai, China.
Shinji AsanoDepartment of Molecular Physiology, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1Noji Higashi, Kusatsu City, Shiga, 525-8577, Japan.
Ritsumeikan University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moesin is expressed in several types of cells including epithelial and endothelial cells. Several groups reported that moesin plays important roles in the regulation of the cellular motility, and the process of internalization of membrane proteins. However, the physiological roles of moesin in the kidney still remain unclear. Herein, we examined the physiological function of moesin in the kidney using moesin knockout (Msn

Indexed as

AnimalsEndocytosisEndothelial CellsExtremitiesKidney MedullaLoop of HenleMaleMembrane MicrodomainsMiceMice, KnockoutMicrofilament ProteinsSolute Carrier Family 12, Member 1Microfilament ProteinsmoesinSlc12a1 protein, mouseSolute Carrier Family 12, Member 1CytoskeletonEndocytosisMineral metabolismRenal physiology

Identifiers

PMID29541861
OpenAlexW2789662367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.