ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2018
Mutations in CsPID encoding a Ser/Thr protein kinase are responsible for round leaf shape in cucumber (Cucumis sativus L.).
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 32 citations in OpenAlex.
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- ABC transporter BrABCG12 mutation results in tender green glossy leaves in Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Mutations in BrMYB31 lead to a glossy phenotype caused by a deficiency in epidermal wax crystals in Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Homeodomain leucine zipper protein controls the lobed leaf formation by modulating auxin distribution in watermelon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Functional Analysis ofInternational journal of molecular sciences · 2024Article
- A mutation in CsGME encoding GDP-mannose 3,5-epimerase results in little and wrinkled leaf in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- A mutation in CsDWF7 gene encoding a delta7 sterol C-5(6) desaturase leads to the phenotype of super compact in cucumber (Cucumis sativus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- BrKCS6 mutation conferred a bright glossy phenotype to Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Role of Brassica orphan gene BrLFM on leafy head formation in Chinese cabbage (Brassica rapa).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Identification of an epicuticular wax crystal deficiency geneFrontiers in plant science · 2023Article
- Multi-model genome-wide association studies of leaf anatomical traits and vein architecture in rice.Frontiers in plant science · 2023Article
- Research Progress on the Leaf Morphology, Fruit Development and Plant Architecture of the Cucumber.Plants (Basel, Switzerland) · 2022Review
- Morphological Characterization and Integrated Transcriptome and Proteome Analysis ofInternational journal of molecular sciences · 2022Article
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- Understanding the molecular mechanism of leaf morphogenesis in vegetable crops conduces to breeding process.Frontiers in plant science · 2022Review
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- Genetic regulation of shoot architecture in cucumber.Horticulture research · 2021Review
- Mapping of a Pale Green Mutant Gene and Its Functional Verification by Allelic Mutations in Chinese Cabbage (Frontiers in plant science · 2021Article
- The SAP function in pistil development was proved by two allelic mutations in Chinese cabbage (Brassica rapa L. ssp. pekinensis).BMC plant biology · 2020Article
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9 authors at 2 institutions in 2 countries.
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Abstract
key messageTwo round-leaf mutants, rl-1 and rl-2, were identified from EMS-induced mutagenesis. High throughput sequencing and map-based cloning suggested CsPID encoding a Ser/Thr protein kinase as the most possible candidate for rl-1. Rl-2 was allelic to Rl-1. Leaf shape is an important plant architecture trait that is affected by plant hormones, especially auxin. In Arabidopsis, PINOID (PID), a regulator for the auxin polar transporter PIN (PIN-FORMED) affects leaf shape formation, but this function of PID in crop plants has not been well studied. From an EMS mutagenesis population, we identified two round-leaf (rl) mutants, C356 and C949. Segregation analysis suggested that both mutations were controlled by single recessive genes, rl-1 and rl-2, respectively. With map-based cloning, we show that CsPID as the candidate gene of rl-1; a non-synonymous SNP in the second exon of CsPID resulted in an amino acid substitution and the round leaf phenotype. As compared in the wild type plant, CsPID had significantly lower expression in the root, leaf and female flowers in C356, which may result in the less developed roots, round leaves and abnormal female flowers, respectively in the rl-1 mutant. Among the three copies of PID genes, CsPID, CsPID2 and CSPID2L (CsPID2-like) in the cucumber genome, CsPID was the only one with significantly differential expression in adult leaves between WT and C356 suggesting CsPID plays a main role in leaf shape formation. The rl-2 mutation in C949 was also cloned, which was due to another SNP in a nearby location of rl-1 in the same CsPID gene. The two round leaf mutants and the work presented herein provide a good foundation for understanding the molecular mechanisms of CsPID in cucumber leaf development.
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