Evidence map›Paper›PMID 29541604›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2018

Single-use membrane adsorbers for endotoxin removal and purification of endogenous polysialic acid from

Ingo de Vries, Sarah Schreiber, Daniel Boßmann, Zawadi Hellmann, Jens Kopatz, Harald Neumann, Sascha Beutel

Abstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Customized chitooligosaccharide production-controlling their lengthFrontiers in bioengineering and biotechnology · 2022
    Article
  4. Accelerated production of α2,8- and α2,9-linked polysialic acid in recombinantBiotechnology reports (Amsterdam, Netherlands) · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ingo de VriesInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.
Sarah SchreiberInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.
Daniel BoßmannInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.
Zawadi HellmannInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.
Jens KopatzInstitute of Reconstructive Neurobiology, University of Bonn, Bonn, Germany.
Harald NeumannInstitute of Reconstructive Neurobiology, University of Bonn, Bonn, Germany.
Sascha BeutelInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polysialic acid (polySia) is a promising molecule for various medical applications (e.g., treatment of inflammatory neurodegenerative diseases). In this study a complete production process for human-identical α-(2,8)-linked polySia was developed using a disposable bioreactor for cultivation of

Indexed as

EndotoxinEscherichia coli K1Membrane adsorberPolysialic acidSingle-use

Identifiers

PMID29541604
PMCPMC5849784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.