Evidence map›Paper›PMID 29541542›Full record

ArticleBrain and behavior2018

Predictors of freezing of gait in Chinese patients with Parkinson's disease.

Ruwei Ou, Qianqian Wei, Bei Cao, Wei Song, Yanbing Hou, Hui Liu, Xiaoqin Yuan, Bi Zhao, Ying Wu, Huifang Shang

Abstract read
In one paragraph

Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Towards the Prevention of Freezing of Gait in Parkinson's Disease.The European journal of neuroscience · 2026
    Review
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  8. Impact of excessive daytime sleepiness on the progression of freezing of gait in de novo Parkinson's disease: a cohort study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
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  16. Association of sleep disturbance and freezing of gait in Parkinson disease: prevention/delay implications.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruwei OuDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Qianqian WeiDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Bei CaoDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Wei SongDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Yanbing HouDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Hui LiuDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Xiaoqin YuanDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Bi ZhaoDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Ying WuDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.
Huifang ShangDepartment of Neurology West China Hospital Sichuan University Chengdu Sichuan China.ORCID 0000-0003-0947-1151

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the clinical predictors of freezing of gait (FOG) in Chinese patients with Parkinson's disease (PD). Methods: This study included 225 patients with PD who completed a three-year follow-up visit. The end-point was the presence of FOG (freezers), which was assessed during the follow-up visit. Group comparisons were conducted, followed by a further forward binary logistic regression analysis. Results: Eighty-five patients with PD (38%) had developed FOG at the end of study. At baseline, freezers exhibited higher age, longer disease duration, higher scores in Unified PD Rating Scale (UPDRS) III and Hamilton Depression/Anxiety Rating Scale, lower Frontal Assessment Battery (FAB) score, higher subscores (e.g., "urgency") and frequencies (e.g., "hallucinations") in Non-Motor Symptoms Scale, higher annual changes in MoCA, UPDRS III and FAB scores, and higher incidences of festination and falls than nonfreezers ( Conclusions: Patients with onset in the lower limbs and the presence of festination, falls, and hallucinations may be prone to develop FOG episodes. FOG also likely occurs with the deterioration of PD severity and visuospatial function.

Indexed as

Accidental FallsAgedAged, 80 and overChinaFemaleGaitGait Disorders, NeurologicHallucinationsHumansLegLogistic ModelsMaleMiddle AgedParkinson DiseaseProspective Studiesfestinationfreezing of gaithallucinationmotor fluctuationParkinson's diseasevisuospatial impairment

Identifiers

PMID29541542
PMCPMC5840456

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.