Evidence map›Paper›PMID 29541533›Full record

Observational studyBrain and behavior2018

Impulse control disorders in Parkinson's: Sleep disorders and nondopaminergic associations.

Samuel Carbunaru, Robert S Eisinger, Adolfo Ramirez-Zamora, Dana Bassan, Amin Cervantes-Arriaga, Mayela Rodriguez-Violante, Daniel Martinez-Ramirez

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The Association of Antidepressant Use and Impulse Control Disorder in Parkinson's Disease.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Observational
  4. Past, present, and future of sleep medicine research in Latin America.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  5. Review
  6. Article
  7. Review
  8. Sleep in Parkinson's Disease with Impulse Control Disorder.Current neurology and neuroscience reports · 2018
    Review
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Samuel CarbunaruDepartment of Neurology Center for Movement Disorders and Neurorestoration University of Florida Gainesville FL USA.ORCID 0000-0001-5297-3611
Robert S EisingerDepartment of Neurology Center for Movement Disorders and Neurorestoration University of Florida Gainesville FL USA.
Adolfo Ramirez-ZamoraDepartment of Neurology Center for Movement Disorders and Neurorestoration University of Florida Gainesville FL USA.
Dana BassanDepartment of Neurology Center for Movement Disorders and Neurorestoration University of Florida Gainesville FL USA.
Amin Cervantes-ArriagaInstituto Nacional de Neurología y Neurocirugía Universidad Nacional Autónoma de México Mexico City México.
Mayela Rodriguez-ViolanteInstituto Nacional de Neurología y Neurocirugía Universidad Nacional Autónoma de México Mexico City México.
Daniel Martinez-RamirezDepartment of Neurology Center for Movement Disorders and Neurorestoration University of Florida Gainesville FL USA.ORCID 0000-0001-8003-0610
University of Florida · USInstituto Nacional de Neurología y Neurocirugía · MX

Funding

Together: Transforming and Translating Discovery to Improve HealthTL1TR001428 · NCATS · UNIVERSITY OF FLORIDA · PI MCCORMACK, WAYNE T. · 2015 to 2023
$3.9M
NCATS NIH HHS TL1 TR001428
6 · The paper itself

Abstract

Objectives: Impulse control disorders (ICDs) are common among patients with Parkinson's disease (PD). Risk factors identified for developing ICDs include young age, family history, and impulsive personality traits. However, the association of these potentially disabling disorders with nondopaminergic drugs and sleep disorders has been understudied. Our objective was to examine the association between ICDs and nondopaminergic medications and sleep disorders. Methods: We conducted an observational study of 53 patients with PD from the National Institute of Neurology and Neurosurgery. ICDs were diagnosed using the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease Rating Scale (QUIP-RS). Patients underwent polysomnography screening to diagnose the presence of sleep disorders. We documented the presence of dopaminergic and nondopaminergic medications, including monoamine oxidase type B inhibitors (MAOBIs), antidepressants, sleep inductors, and antipsychotics. Results: ICDs were reported in 18.9% of the patients ( Conclusion: Antidepressants and sleep inductors were significant predictors for individual QUIP-RS items and subscores. Our results suggest that nondopaminergic drugs commonly used for PD may be associated with impulse control disorders. We did not identify a relationship between ICDs and polysomnography-confirmed sleep disorders in patients with PD. Larger and longitudinal studies are needed to confirm our results.

Indexed as

AdultAgedAged, 80 and overAntidepressive AgentsAntiparkinson AgentsDisruptive, Impulse Control, and Conduct DisordersFemaleHumansImpulsive BehaviorMaleMiddle AgedMonoamine Oxidase InhibitorsParkinson DiseaseRisk FactorsSleep Aids, PharmaceuticalSleep Wake DisordersAntidepressive AgentsAntiparkinson AgentsMonoamine Oxidase InhibitorsSleep Aids, Pharmaceuticalimpulse control disordersnondopaminergic medicationsParkinson's diseasesleep disorders

Identifiers

PMID29541533
PMCPMC5840436
OpenAlexW2793790523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.